Stelazine Side Effects
Generic name: trifluoperazine
Note: This document contains side effect information about trifluoperazine. Some of the dosage forms listed on this page may not apply to the brand name Stelazine.
Some side effects of Stelazine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to trifluoperazine: oral tablets
Side effects include:
Extrapyramidal reactions (e.g., Parkinson-like symptoms, dystonia, akathisia), drowsiness, fatigue, muscular weakness, insomnia, blurred vision, skin reactions or rash, anorexia, dry mouth, hypotension, amenorrhea, galactorrhea.
For Healthcare Professionals
Applies to trifluoperazine: compounding powder, intramuscular solution, oral concentrate, oral tablet
Nervous system side effects including motor restlessness, jitteriness, spasm of the neck muscles, rigidity of back muscles, opisthotonos, carpopedal spasm, hyperreflexia, dystonia, akathisia, dyskinesia, grand mal and petit mal seizures, trismus, protrusion of the tongue, drooling, tremors, shuffling gait, and chewing movements have been frequently reported.
Cardiovascular side effects including tachycardia, cardiac arrest, hypotension, hypertension, orthostatic hypotension, light-headedness, increased pulse rate, EKG changes, and syncope have been reported.
Hematologic side effects including agranulocytosis, thrombocytopenia, pancytopenia, eosinophilia, hemolytic anemia, aplastic anemia, and leukopenia have rarely been reported.
Hepatic side effects including hepatocellular injury, jaundice, biliary stasis, and hepatitis have rarely been reported.
Respiratory side effects including dyspnea, laryngeal edema, and asthma have been infrequently reported.
Genitourinary side effects including urinary retention, increase in prolactin levels, galactorrhea, amenorrhea, gynecomastia, false-positive pregnancy tests, menstrual irregularity, ejaculatory disorders, and impotence have been reported.
Gastrointestinal side effects including nausea, vomiting, obstipation, and constipation have been reported.
Dermatologic side effects including dermatitis, photosensitivity, itching, erythema, urticaria, eczema, exfoliative dermatitis, edema, pruritus, rash, alopecia, skin pigmentation, epithelial keratopathy, and seborrhea have been reported.
Endocrine side effects including hyperglycemia, hypoglycemia, and glycosuria have been reported.
Ocular side effects including blurred vision, oculogyric movement, ptosis, pigmentary retinopathy, and lenticular pigmentation have been reported.
General side effects including dry mouth, weight gain, increased appetite, headache, and hyperpyrexia have been reported.
Psychiatric side effects including reactivation of psychotic processes and catatonic-like states have been infrequently reported.
Musculoskeletal side effects including a case of laryngeal dystonia have been reported.
More Stelazine resources
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