Stelazine Side Effects

Generic Name: trifluoperazine

Note: This page contains side effects data for the generic drug trifluoperazine. It is possible that some of the dosage forms included below may not apply to the brand name Stelazine.

It is possible that some side effects of Stelazine may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to trifluoperazine: oral tablets

Side effects include:

Extrapyramidal reactions (e.g., Parkinson-like symptoms, dystonia, akathisia), drowsiness, fatigue, muscular weakness, insomnia, blurred vision, skin reactions or rash, anorexia, dry mouth, hypotension, amenorrhea, galactorrhea.

For Healthcare Professionals

Applies to trifluoperazine: compounding powder, intramuscular solution, oral concentrate, oral tablet

Nervous system

Nervous system side effects including motor restlessness, jitteriness, spasm of the neck muscles, rigidity of back muscles, opisthotonos, carpopedal spasm, hyperreflexia, dystonia, akathisia, dyskinesia, grand mal and petit mal seizures, trismus, protrusion of the tongue, drooling, tremors, shuffling gait, and chewing movements have been frequently reported.

Cardiovascular

Cardiovascular side effects including tachycardia, cardiac arrest, hypotension, hypertension, orthostatic hypotension, light-headedness, increased pulse rate, EKG changes, and syncope have been reported.

Hematologic

Hematologic side effects including agranulocytosis, thrombocytopenia, pancytopenia, eosinophilia, hemolytic anemia, aplastic anemia, and leukopenia have rarely been reported.

Hepatic

Hepatic side effects including hepatocellular injury, jaundice, biliary stasis, and hepatitis have rarely been reported.

Respiratory

Respiratory side effects including dyspnea, laryngeal edema, and asthma have been infrequently reported.

Genitourinary

Genitourinary side effects including urinary retention, increase in prolactin levels, galactorrhea, amenorrhea, gynecomastia, false-positive pregnancy tests, menstrual irregularity, ejaculatory disorders, and impotence have been reported.

Gastrointestinal

Gastrointestinal side effects including nausea, vomiting, obstipation, and constipation have been reported.

Dermatologic

Dermatologic side effects including dermatitis, photosensitivity, itching, erythema, urticaria, eczema, exfoliative dermatitis, edema, pruritus, rash, alopecia, skin pigmentation, epithelial keratopathy, and seborrhea have been reported.

Endocrine

Endocrine side effects including hyperglycemia, hypoglycemia, and glycosuria have been reported.

Ocular

Ocular side effects including blurred vision, oculogyric movement, ptosis, pigmentary retinopathy, and lenticular pigmentation have been reported.

General

General side effects including dry mouth, weight gain, increased appetite, headache, and hyperpyrexia have been reported.

Psychiatric

Psychiatric side effects including reactivation of psychotic processes and catatonic-like states have been infrequently reported.

Musculoskeletal

Musculoskeletal side effects including a case of laryngeal dystonia have been reported.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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