Spironolactone/hydrochlorothiazide Side Effects

Please note - some side effects for Spironolactone/hydrochlorothiazide may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Spironolactone/hydrochlorothiazide - for the Consumer

Spironolactone/hydrochlorothiazide

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Spironolactone/hydrochlorothiazide:

Constipation; diarrhea; dizziness; headache; loss of appetite; nausea; stomach upset or cramping; tiredness; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur when using Spironolactone/hydrochlorothiazide:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody, black, or tarry stools; burning, numbness, or tingling; confusion; dark urine; decreased coordination; decreased sexual ability; decreased urination or change in the amount of urine produced; dry mouth; excessive thirst; eye pain; fainting; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; leg or muscle cramps, pain, or weakness; menstrual changes; mental or mood changes; red, swollen, blistered, or peeling skin; restlessness; severe or persistent dizziness, weakness, or tiredness; severe or persistent nausea or vomiting; sluggishness; stomach pain; unusual bruising or bleeding; unusual drowsiness; unusual weight loss; vision changes (eg, blurred vision, decreased vision clearness); vomit that looks like coffee grounds; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

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