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Sodium thiosulfate Side Effects

It is possible that some side effects of sodium thiosulfate may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to sodium thiosulfate: intravenous solution

As well as its needed effects, sodium thiosulfate may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking sodium thiosulfate, check with your doctor immediately:

Symptoms of overdose
  • Agitation
  • blurred vision
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • mental changes
  • muscle cramps
  • nausea and vomiting
  • pain in the joints
  • ringing in the ears

For Healthcare Professionals

Applies to sodium thiosulfate: compounding powder, intravenous solution

Gastrointestinal

Frequency not reported: Nausea, vomiting, diarrhea, osmotic disturbances[Ref]

Nervous system

Frequency not reported: Headache, disorientation, salty taste in mouth, warm sensation over body[Ref]

Cardiovascular

Frequency not reported: Hypotension[Ref]

Psychiatric

Frequency not reported: Psychotic behavior including agitation, delusions, and hallucinations[Ref]

Musculoskeletal

Frequency not reported: Arthralgia, hyperreflexia, muscle cramps[Ref]

Hematologic

Frequency not reported: Prolonged bleeding time[Ref]

Other

Frequency not reported: Tinnitus[Ref]

Ocular

Frequency not reported: Blurred vision[Ref]

Genitourinary

Frequency not reported: Diuretic effects[Ref]

References

1. Cerner Multum, Inc. "Australian Product Information." O 0

2. "Product Information. Sodium Thiosulfate (sodium thiosulfate)." American Regent Laboratories Inc, Shirley, NY.

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