Simvastatin and sitagliptin Side Effects
Please note - some side effects for Simvastatin and sitagliptin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Side Effects by Body System - for Healthcare Professionals
Applies to: oral tablet
Endocrine side effects have included hypoglycemia, pancreatitis, acute pancreatitis, including fatal and nonfatal hemorrhagic and necrotizing pancreatitis, hepatitis/jaundice, fatal and nonfatal hepatic failure, and hepatic enzyme elevations.
Gastrointestinal side effects have included constipation, gastritis, abdominal pain, nausea, dyspepsia, flatulence, and diarrhea.
Musculoskeletal side effect shave included muscle cramps, myalgia, arthralgia, and myopathy/rhabdomyolysis.
Respiratory side effects have included bronchitis, sinusitis, upper respiratory tract infection, nasopharyngitis, and interstitial lung disease.
Nervous system side effects have included headache, insomnia, asthenia, paresthesia, dizziness, peripheral neuropathy, vertigo, and cognitive impairment (e.g., memory loss, forgetfulness, amnesia, memory impairment, confusion).
Hypersensitivity side effects have included reactions such as anaphylaxis, angioedema, rash, urticaria, cutaneous vasculitis, and exfoliative skin conditions including Stevens-Johnson syndrome.
Cardiovascular side effects have included atrial fibrillation.
Genitourinary side effects have included urinary tract infection and erectile dysfunction.
Dermatologic side effects have included eczema, rash, pruritus, alopecia, and a variety of skin changes (e.g., nodules, discoloration, dryness of skin/mucous membranes, changes to hair/nails).
General side effects have included edema and swelling.
Renal side effects have included worsening renal function, including acute renal failure (sometimes requiring dialysis).Top
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