Salagen Side Effects

Generic Name: pilocarpine

Note: This document contains side effect information about pilocarpine. Some of the dosage forms listed on this page may not apply to the brand name Salagen.

Some side effects of Salagen may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to pilocarpine: oral tablet

Along with its needed effects, pilocarpine (the active ingredient contained in Salagen) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking pilocarpine:

Symptoms of overdose
  • Chest pain
  • confusion
  • diarrhea (continuing or severe)
  • fainting
  • fast, slow, or irregular heartbeat (continuing or severe)
  • headache (continuing or severe)
  • nausea or vomiting (continuing or severe)
  • shortness of breath or troubled breathing
  • stomach cramps or pain
  • tiredness or weakness (continuing or severe)
  • trembling or shaking (continuing or severe)
  • trouble seeing (continuing or severe)

Some side effects of pilocarpine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Chills
  • cough
  • diarrhea
  • feeling of warmth or heat
  • fever
  • flushing or redness of skin especially on face and neck
  • increased need to urinate
  • indigestion
  • joint pain
  • muscle aches and pains
  • nausea
  • passing urine more often
  • runny nose
  • unusual tiredness or weakness
  • Sweating
Less common or rare
  • fast heartbeat
  • headache
  • holding more body water
  • swelling of face, fingers, ankles, or feet
  • trembling or shaking
  • trouble swallowing
  • trouble seeing
  • unusual weak feeling
  • voice change
  • vomiting

For Healthcare Professionals

Applies to pilocarpine: compounding crystal, compounding powder, oral tablet

Gastrointestinal

Gastrointestinal side effects commonly reported have included nausea (6% to 15%), diarrhea (4% to 7%), dyspepsia (7%), abdominal pain (4%), and vomiting (4%). Anorexia, increased appetite, cholelithiasis, flatulence, gastritis, gastroenteritis, gastrointestinal disorder, and tongue disorder have been reported rarely.

Respiratory

Respiratory side effects have included rhinitis (5% to 14%), sinusitis (4%), and pharyngitis (2%). Esophagitis, increased sputum, stridor, yawning, bronchitis, dyspnea, hiccup, laryngismus, laryngitis, and voice alteration have been reported infrequently.

Endocrine

Endocrine side effects have included sweating (29% to 68%), lacrimation (6%), and increased salivation (3%).

Cardiovascular

Cardiovascular side effects have included hypertension (3%), angina pectoris, arrhythmia, electrocardiogram abnormality, hypotension, myocardial infarction, tachycardia, bradycardia, palpitations, and syncope.

Nervous system

Nervous system side effects commonly reported have included asthenia (6% to 12%) and dizziness (5% to 12%). Aphasia, confusion, abnormal dreams, hyperkinesia, hypesthesia, insomnia, myalgia, paresthesias, abnormal thinking, speech disorder, twitching, and tremor have been reported less frequently.

Ocular

Ocular side effects have included amblyopia, cataract, conjunctivitis, dry eyes, blurred vision, eye disorder, eye pain, eye hemorrhage, glaucoma, retinal disorder, and abnormal vision.

Genitourinary

Genitourinary side effects have included dysuria, metrorrhagia, urinary impairment, urinary incontinence, urinary tract infection, vaginitis, breast pain, mastitis, menorrhagia, ovarian disorder, pyuria, salpingitis, urethral pain, urinary urgency, vaginal hemorrhage, and vaginal moniliasis.

Psychiatric

Psychiatric side effects have included anxiety, confusion, depression, abnormal dreams, somnolence, emotional lability, insomnia, and nervousness.

Hematologic

Hematologic side effects have included leukopenia, lymphadenopathy, hematuria, abnormal platelets, thrombocythemia, thrombocytopenia, thrombosis, and abnormal WBC.

Metabolic

Metabolic side effects have included hypoglycemia.

Dermatologic

Dermatologic side effects have included seborrhea.

Other

Other infrequently reported side effects have included cyst, neck pain, neck rigidity, photosensitivity reaction, body odor, taste loss, taste perversion, voice alteration, tongue disorder, tooth disorder, increased cough, fever, and lab test abnormalities.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Hide
(web2)