Robaxin Side Effects

Generic Name: methocarbamol

Please note - some side effects for Robaxin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Robaxin - for the Consumer

Robaxin

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Robaxin:

Blurred vision; confusion; dizziness; double vision; drowsiness; fainting; fever; flushing; headache; indigestion; lightheadedness; metallic taste in mouth; mild muscle incoordination; nasal stuffiness; nausea; pain and sloughing at the injection site; "pink eye;" rapid eye movement; sleeplessness; swelling; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); memory loss; seizures; slow heartbeat; yellowing of the skin or eyes.

Robaxin Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Robaxin Tablets:

Blurred vision; dizziness; drowsiness; eye redness or irritation; fever; headache; hives; lightheadedness; nasal stuffiness; nausea.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting; seizures; yellowing of the skin or eyes.

Robaxin Side Effects - for the Professional

Robaxin

The following adverse reactions have been reported coincident with the administration of methocarbamol. Some events may have been due to an overly rapid rate of intravenous injection.

Body as a Whole

Anaphylactic reaction, angioneurotic edema, fever, headache

Cardiovascular System

Bradycardia, flushing, hypotension, syncope, thrombophlebitis

In most cases of syncope there was spontaneous recovery. In others, epinephrine, injectable steroids, and/or injectable antihistamines were employed to hasten recovery.

Digestive System

Dyspepsia, jaundice (including cholestatic jaundice), nausea and vomiting

Hemic and Lymphatic System

Leukopenia

Immune System

Hypersensitivity reactions

Nervous System

Amnesia, confusion, diplopia, dizziness or light-headedness, drowsiness, insomnia, mild muscular incoordination, nystagmus, sedation, seizures (including grand mal), vertigo

The onset of convulsive seizures during intravenous administration of methocarbamol has been reported in patients with seizure disorders. The psychic trauma of the procedure may have been a contributing factor. Although several observers have reported success in terminating epileptiform seizures with Robaxin Injectable, its administration to patients with epilepsy is not recommended.

Skin and Special Senses

Blurred vision, conjunctivitis, nasal congestion, metallic taste, pruritus, rash, urticaria

Other

Pain and sloughing at the site of injection

Robaxin Tablets

Adverse reactions reported coincident with the administration of methocarbamol include:

Body as a whole: Anaphylactic reaction, angioneurotic edema, fever, headache

Cardiovascular system: Bradycardia, flushing, hypotension, syncope, thrombophlebitis

Digestive system: Dyspepsia, jaundice (including cholestatic jaundice), nausea and vomiting

Hemic and lymphatic system: Leukopenia

Immune system: Hypersensitivity reactions

Nervous system: Amnesia, confusion, diplopia, dizziness or lightheadedness, drowsiness, insomnia, mild muscular incoordination, nystagmus, sedation, seizures (including grand mal), vertigo

Skin and special senses: Blurred vision, conjunctivitis, nasal congestion, metallic taste, pruritus, rash, urticaria

Side Effects by Body System

Cardiovascular

Cardiovascular side effects have included syncope, hypotension, and bradycardia.

Nervous system

Nervous system side effects have included dizziness, lightheadedness, vertigo, headache, drowsiness, fainting, and mild muscular incoordination. Convulsions have been reported with intravenous administration, especially in patients with a history of epilepsy.

Dermatologic

Dermatologic side effects have included urticaria, pruritus, rash, sloughing, thrombophlebitis, and pain at the injection site.

Ocular

Ocular side effects have included blurred vision, conjunctivitis, nystagmus, and diplopia.

Respiratory

Respiratory side effects have included nasal congestion, bronchospasm, and anaphylaxis.

Gastrointestinal

Gastrointestinal side effects have included gastrointestinal upset, anorexia, and adynamic ileus.

Other

Other side effects have included metallic taste and fever.

Effects on lab tests have included a possible color interference in certain screening tests for 5-hydroxyindoleacetic acid (5-HIAA) and vanillylmandelic acid (VMA).

Hematologic

Hematologic side effects have included hemolysis, particularly with intravenous injection.

Renal

Methocarbamol vials for injection contain polyethylene glycol 300 (PEG 300). Larger amounts of PEG 300 can increase preexisting renal acidosis and urea retention in patients with renal insufficiency.

Renal side effects including urine discoloration (black, blue, brown, or green) have been reported after oral administration in some patients.

General

General side effects have included angioneurotic edema.

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