Robaxin-750 Side Effects
Generic name: methocarbamol
Note: This document contains side effect information about methocarbamol. Some of the dosage forms listed on this page may not apply to the brand name Robaxin-750.
Some side effects of Robaxin-750 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to methocarbamol: oral tablet
Other dosage forms:
Along with its needed effects, methocarbamol (the active ingredient contained in Robaxin-750) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking methocarbamol:Incidence not known
- Abdominal or stomach pain
- black, tarry stools
- changes in skin color
- chest pain or discomfort
- clay-colored stools
- dark urine
- difficulty swallowing
- fast heartbeat
- feeling of warmth
- joint or muscle pain
- large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- lightheadedness, dizziness, or fainting
- loss of appetite
- loss of bladder control
- loss of consciousness
- loss of memory
- numbness or tingling of face, hands, or feet
- pain, tenderness, or swelling of foot or leg
- painful or difficult urination
- problems with memory
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness and soreness of eyes
- redness of the face, neck, arms, and occasionally, upper chest
- relaxed and calm
- shortness of breath
- skin rash
- slow or irregular heartbeat
- sore throat
- sores, ulcers, or white spots on lips or in mouth
- swollen glands
- tightness in chest
- total body jerking
- unpleasant breath odor
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting of blood
- yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur while taking methocarbamol:Symptoms of Overdose
- Shaking or jerking of one area or side of the body
Some side effects of methocarbamol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Incidence not known
- Acid or sour stomach
- double vision
- feeling of constant movement of self or surroundings
- mood or mental changes
- seeing double
- sensation of spinning
- stomach discomfort, upset, or pain
- trouble sleeping
- unable to sleep
- uncontrolled eye movements
For Healthcare Professionals
Applies to methocarbamol: injectable solution, oral tablet
Cardiovascular side effects have included syncope, hypotension, and bradycardia.
Nervous system side effects have included dizziness, lightheadedness, vertigo, headache, drowsiness, fainting, and mild muscular incoordination. Convulsions have been reported with intravenous administration, especially in patients with a history of epilepsy.
Dermatologic side effects have included urticaria, pruritus, rash, sloughing, thrombophlebitis, and pain at the injection site.
Ocular side effects have included blurred vision, conjunctivitis, nystagmus, and diplopia.
Respiratory side effects have included nasal congestion, bronchospasm, and anaphylaxis.
Gastrointestinal side effects have included gastrointestinal upset, anorexia, and adynamic ileus.
Other side effects have included metallic taste and fever.
Effects on lab tests have included a possible color interference in certain screening tests for 5-hydroxyindoleacetic acid (5-HIAA) and vanillylmandelic acid (VMA).
Hematologic side effects have included hemolysis, particularly with intravenous injection.
Methocarbamol (the active ingredient contained in Robaxin-750) vials for injection contain polyethylene glycol 300 (PEG 300). Larger amounts of PEG 300 can increase preexisting renal acidosis and urea retention in patients with renal insufficiency.
Renal side effects including urine discoloration (black, blue, brown, or green) have been reported after oral administration in some patients.
General side effects have included angioneurotic edema.
More Robaxin-750 resources
- Robaxin-750 Advanced Consumer (Micromedex) - Includes Dosage Information
- Methocarbamol Prescribing Information (FDA)
- Methocarbamol Professional Patient Advice (Wolters Kluwer)
- Methocarbamol Monograph (AHFS DI)
- methocarbamol MedFacts Consumer Leaflet (Wolters Kluwer)
- Robaxin Prescribing Information (FDA)
- Robaxin Consumer Overview
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