Robaxin-750 Side Effects

Generic name: methocarbamol

Note: This document contains side effect information about methocarbamol. Some of the dosage forms listed on this page may not apply to the brand name Robaxin-750.

Some side effects of Robaxin-750 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to methocarbamol: oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking methocarbamol (the active ingredient contained in Robaxin-750) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using methocarbamol and call your doctor at once if you have a serious side effect such as:

• fever, chills, flu symptoms;

• slow heart rate;

• feeling like you might pass out;

• seizure (convulsions); or

• jaundice (yellowing of your skin or eyes).

Less serious side effects of methocarbamol may include:

• dizziness, spinning sensation, drowsiness;

• headache, confusion, memory problems, loss of balance or coordination;

• nausea, vomiting, upset stomach;

• flushing (warmth, redness, or tingly feeling);

• blurred vision, double vision, eye redness;

• sleep problems (insomnia);

• stuffy nose; or

• mild itching or rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to methocarbamol: injectable solution, oral tablet

Cardiovascular

Cardiovascular side effects have included syncope, hypotension, and bradycardia.

Nervous system

Nervous system side effects have included dizziness, lightheadedness, vertigo, headache, drowsiness, fainting, and mild muscular incoordination. Convulsions have been reported with intravenous administration, especially in patients with a history of epilepsy.

Dermatologic

Dermatologic side effects have included urticaria, pruritus, rash, sloughing, thrombophlebitis, and pain at the injection site.

Ocular

Ocular side effects have included blurred vision, conjunctivitis, nystagmus, and diplopia.

Respiratory

Respiratory side effects have included nasal congestion, bronchospasm, and anaphylaxis.

Gastrointestinal

Gastrointestinal side effects have included gastrointestinal upset, anorexia, and adynamic ileus.

Other

Other side effects have included metallic taste and fever.

Effects on lab tests have included a possible color interference in certain screening tests for 5-hydroxyindoleacetic acid (5-HIAA) and vanillylmandelic acid (VMA).

Hematologic

Hematologic side effects have included hemolysis, particularly with intravenous injection.

Renal

Methocarbamol (the active ingredient contained in Robaxin-750) vials for injection contain polyethylene glycol 300 (PEG 300). Larger amounts of PEG 300 can increase preexisting renal acidosis and urea retention in patients with renal insufficiency.

Renal side effects including urine discoloration (black, blue, brown, or green) have been reported after oral administration in some patients.

General

General side effects have included angioneurotic edema.

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