Rivastigmine transdermal Side Effects

Please note - some side effects for Rivastigmine transdermal may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects by Body System - for Healthcare Professionals

Applies to: oral capsule; oral solution; transdermal film, extended release

Gastrointestinal

Gastrointestinal effects including nausea (47%), vomiting (31%), diarrhea (19%), anorexia (17%), abdominal pain (13%), dyspepsia (9%), constipation (5%), flatulence (4%), and eructation (2%) have been reported. There has also been one postmarketing report of severe vomiting with esophageal rupture following inappropriate reinitiation of treatment. Postmarketing reports have included duodenal ulcers.

When treatment is interrupted for longer than several days, treatment must be reinitiated with the lowest daily dose to reduce the possibility of severe vomiting and its potentially serious sequelae.

Nervous system

Nervous system side effects including dizziness (21%), headache (17%), somnolence (5%), tremor (4%), increased sweating (4%), and syncope (3%) have been reported. Postmarketing reports have included confusion.

General

General side effects including accidental trauma (10%), fatigue (9%), asthenia (6%), malaise (5%), influenza-like symptoms (3%), and decreased weight (3%) have been reported.

Psychiatric

Psychiatric side effects including insomnia (9%), confusion (8%), depression (6%), anxiety (5%), hallucination (4%), and aggressive reaction (3%) have been reported.

Dermatologic

Dermatologic side effects including Stevens-Johnson syndrome have been reported. A case of erythematous macropapular eruption due to rivastigmine therapy has also been reported.

Genitourinary

Genitourinary side effects including urinary tract infection (7%) have been reported.

Respiratory

Respiratory side effects including rhinitis (4%) have been reported.

Cardiovascular

Cardiovascular side effects including hypertension (3%) have been reported. A case of complete atrioventricular block has also been reported.

Hepatic

Hepatic side effects have included abnormal liver function tests.

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