Raxar Side Effects
Generic Name: grepafloxacin
Note: This document contains side effect information about grepafloxacin. Some of the dosage forms listed on this page may not apply to the brand name Raxar.
Some side effects of Raxar may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to grepafloxacin: oral tablet
If you experience any of the following serious side effects, stop taking grepafloxacin (the active ingredient contained in Raxar) and seek emergency medical attention:
an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
irregular or slow heartbeats;
confusion or hallucinations;
liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or
muscle or joint pain.
If you experience any of the following less serious side effects, continue taking grepafloxacin and talk to your doctor:
nausea, vomiting, or diarrhea;
headache, lightheadedness, drowsiness, or insomnia;
ringing in your ears; or
increased sensitivity of the skin to sunlight.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
For Healthcare Professionals
Applies to grepafloxacin: oral tablet
Percentages below refer to patients treated on multiple-dose regimens.
Nausea and taste perversion (e.g. medicinal taste) are the most common adverse effects of grepafloxacin (the active ingredient contained in Raxar) occurring in as many as 11% to 16%, and 9% to 18% of patients, respectively. Other gastrointestinal effects including diarrhea, abdominal pain, vomiting, dyspepsia, anorexia, dry mouth, and constipation have been reported in 1% to 4% of patients. Abnormal stools, cheilitis, dysphagia, eructation, flatulence, gastritis, gastrointestinal disorder, gingivitis, glossitis, increased appetite, melena, mouth ulceration, oral moniliasis, rectal disorder, rectal hemorrhage, stomatitis, tenesmus, thirst, tongue discoloration, tongue disorder, and tongue edema have been reported in less than 1% of patients.
Nervous system side effects have included headache, dizziness, insomnia, somnolence, and nervousness in 1% to 5% of patients. Abnormal dreams, abnormal gait, agitation, anxiety, confusion, depression, emotional lability, hallucinations, hyperkinesia, hypoesthesia, hypokinesia, paresthesia, speech disorder, stupor, thinking abnormality, tremor, and vertigo have been reported in less than 1% of patients.
Genitourinary side effects have included vaginitis and leukorrhea in up to 3% of patients. Albuminuria, balanitis, dysuria, hematuria, impotence, polyuria, urethral pain, uricaciduria, urinary frequency, urinary tract disorder, impaired urination, urine abnormality, and vulvovaginal disorder have been reported in less than 1% of patients.
Dermatologic side effects have included pruritus and rash in 1% to 2% of treated patients. Acne, alopecia, dry skin, epidermal necrolysis, exfoliative dermatitis, fungal dermatitis, herpes simplex, macropapular rash, skin disorder, sweating, urticaria, and vesiculobullous rash have been reported in less than 1% of patients.
Non-specific side effects have included asthenia and pain in 1% to 2% of treated patients. Back pain, body odor, chest pain, chills, facial edema, fever, malaise, neck rigidity, and pelvic pain have been reported in less than 1% of treated patients.
Cardiovascular side effects have included arrhythmia, hypotension, palpitations, peripheral vascular disorder, postural hypotension, syncope, tachycardia, and vasodilation in less than 1% of patients.
Hematologic side effects have been reported in less than 1% of patients and have included anemia, eosinophilia, hypochromic anemia, leukocytosis, leukopenia, lymphadenopathy, lymphocytosis, lymphoma-like reaction, decrease in prothrombin, increase in prothrombin, reticuloendothelial hyperplasia, thrombocytopenia, and increased thromboplastin.
Metabolic side effects have included dehydration, edema, electrolyte abnormality, gout, hyperglycemia, hyperlipidemia, hypernatremia, hyperuricemia, peripheral edema, and weight loss in less than 1% of patients.
Musculoskeletal side effects have been reported in less than 1% of patients and have included arthralgia and myalgia.
Respiratory side effects have included asthma, atelectasis, bronchitis, dyspnea, epistaxis, hemoptysis, increased cough, laryngismus, pharyngitis, pleural effusion, rhinitis, and increased sputum in less than 1% of patients.
Ocular side effects have included amblyopia, conjunctivitis, dry eyes, eye pain, lacrimation disorder, and photophobia in less than 1% of patients.
Deafness, ear disorder, parosmia, taste loss and tinnitus have been reported in less than 1% of patients.
Hepatic side effects have included abnormal liver function tests in greater than 1% of patients.
More about Raxar (grepafloxacin)
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