Propine Side Effects

Generic Name: dipivefrin ophthalmic

Note: This document contains side effect information about dipivefrin ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Propine.

Some side effects of Propine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to dipivefrin ophthalmic: ophthalmic solution

Along with its needed effects, dipivefrin ophthalmic (the active ingredient contained in Propine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking dipivefrin ophthalmic:

Rare
  • Fast or irregular heartbeat
  • increase in blood pressure
  • itching, pain, redness, or swelling of eye or eyelid (severe), or other irritation of the eye
  • skin rash or hives
  • watering of eyes (severe and continuing)

Some side effects of dipivefrin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Blurred vision
  • burning or stinging of the eye
  • headache
  • increased sensitivity of eyes to light
  • large pupils

For Healthcare Professionals

Applies to dipivefrin ophthalmic: ophthalmic solution

Ocular

Ocular side effects have included injection (6.5%), stinging (6%), and burning (6%). Follicular conjunctivitis and mydriasis have been reported rarely. Corneal vascularization or vesicles, eyelid ectropion, papillary conjunctivitis, blepharoconjunctivitis, macular edema, corneal toxicity (dendritic keratitis, punctate keratitis, or epitheliopathy), and blurred vision have also been reported.

Ocular side effects associated with ocular administration of epinephrine have included conjunctival and corneal adrenochrome deposits.

Some long-term studies have reported observations of follicular conjunctivitis in almost all patients with up to 40% classified as severe reactions.

Cardiovascular

Cardiovascular side effects have included slight increases in heart rate and diastolic blood pressure.

Cardiovascular side effects associated with ocular epinephrine have included tachycardia, arrhythmias, and hypertension.

Most placebo-controlled studies have reported mild average increases in heart rate (3 to 4 beats/min--with or without palpitations) or diastolic blood pressure (1 to 5 mm Hg) associated with dipivefrin.

Nervous system

Nervous system side effects have included headache and dizziness.

Hypersensitivity

Hypersensitivity reactions have included bronchospasm associated with a formulation containing bisulfite preservative.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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