Promethazine VC Side Effects

Generic Name: phenylephrine / promethazine

Note: This page contains side effects data for the generic drug phenylephrine / promethazine. It is possible that some of the dosage forms included below may not apply to the brand name Promethazine VC.

It is possible that some side effects of Promethazine VC may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to phenylephrine / promethazine: oral syrup

If you experience any of the following serious side effects, stop taking phenylephrine and promethazine and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or

  • uncontrollable movements of the eyes, lips, tongue, face, arms, or legs.

Other, less serious side effects may be more likely to occur. Continue to take phenylephrine and promethazine and talk to your doctor if you experience

  • dizziness, drowsiness, sleepiness, or confusion;

  • restlessness or irritability;

  • blurred vision or a dry mouth;

  • nausea or vomiting; or

  • increased skin sensitivity to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

For Healthcare Professionals

Applies to phenylephrine / promethazine: oral syrup

Cardiovascular

Cardiovascular side effects have included increased or decreased blood pressure.

Nervous system

Nervous system side effects have included sedation, sleepiness, dizziness, confusion, disorientation, restlessness, anxiety, nervousness, tremor, weakness, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion.

Ocular

Ocular side effects have included blurred vision.

Gastrointestinal

Gastrointestinal side effects have included dry mouth, nausea, and vomiting.

Hematologic

Hematologic side effects have included rare cases of leukopenia, thrombocytopenia, and agranulocytosis.

Dermatologic

Dermatologic side effects have included rash and rarely photosensitivity.

Respiratory

Respiratory side effects have included respiratory distress.

More about Promethazine VC (phenylephrine / promethazine)

Consumer resources

Professional resources

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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