Precedex Side Effects
Generic name: dexmedetomidine
Note: This document contains side effect information about dexmedetomidine. Some of the dosage forms listed on this page may not apply to the brand name Precedex.
Some side effects of Precedex may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to dexmedetomidine: parenteral injection concentrate
Side effects include:
Hypotension, hypertension, nausea, bradycardia, fever, vomiting, hypoxia, tachycardia, anemia.
For Healthcare Professionals
Applies to dexmedetomidine: intravenous solution
Cardiovascular
Cardiovascular side effects include hypotension (up to 54%), hypertension (up to 16%), bradycardia (up to 14%), atrial fibrillation (7%) and tachycardia (up to 5%).
Gastrointestinal
Gastrointestinal side effects include nausea (up to 11%), dry mouth (3%), and vomiting.
Respiratory
Respiratory side effects have included respiratory depression (37%) hypoxia (up to 6%), pleural effusion (3%), bradypnea (2%), and pulmonary edema (2%). Acute Respiratory Distress Syndrome (ARDS) and respiratory failure have been associated with infusions greater than 24 hours in duration.
Hematologic
Hematologic side effects include anemia (3%), leukocytosis (2%) and anemia.
General
General side effects include pain (3%), thirst (2%), and fever.
Genitourinary
Genitourinary side effects include oliguria (2%).
Dermatologic
Dermatologic side effects including a case of severe rash have been reported.
Nervous system
Nervous system side effects have included agitation associated with infusions greater than 24 hours in duration.
More Precedex resources
- Precedex Prescribing Information (FDA)
- Precedex Monograph (AHFS DI)
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