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Side Effects > Podofilox

Podofilox Side Effects

Please note - some side effects for Podofilox may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).


For the consumer

For the professional

Side Effects of Podofilox - for the consumer


Podofilox Gel

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Podofilox Gel:

Headache; mild burning, inflammation, stinging, pain, or redness.

Seek medical attention right away if any of these SEVERE side effects occur when using Podofilox Gel:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding, swelling, or severe or prolonged pain, burning, or itching at the application site.


Podofilox Solution

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Podofilox Solution:

Headache; mild burning, inflammation, stinging, pain, or redness.

Seek medical attention right away if any of these SEVERE side effects occur when using Podofilox Solution:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding, swelling, or severe or prolonged pain, burning, or itching at the application site; blood in the urine.

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For the professional


Podofilox

In clinical trials, the following local adverse reactions were reported at some point during treatment.

Adverse Experience Males Females
  Burning 64% 78%
  Pain 50% 72%
  Inflammation 71% 63%
  Erosion 67% 67%
  Itching 50% 65%

Reports of burning and pain were more frequent and of greater severity in women than in men.

Adverse effects reported in less than 5% of the patients included pain with intercourse, insomnia, tingling, bleeding, tenderness, chafing, malodor, dizziness, scarring, vesicle formation, crusting edema, dryness/peeling, foreskin irretraction, hematuria, vomiting and ulceration.

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