Phosphate Laxative Side Effects
Generic Name: sodium biphosphate / sodium phosphate
Note: This page contains side effects data for the generic drug sodium biphosphate / sodium phosphate. It is possible that some of the dosage forms included below may not apply to the brand name Phosphate Laxative.
It is possible that some side effects of Phosphate Laxative may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to sodium biphosphate / sodium phosphate: tablets
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking sodium biphosphate / sodium phosphate:
Mild stomach pain; nausea; stomach bloating; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; unusual hoarseness); burning, numbness, or tingling of the lips or tongue; fainting; irregular heartbeat; seizures; severe or persistent nausea or vomiting; severe or persistent stomach bloating, cramping, or pain; symptoms of dehydration (eg, dizziness, headache, sluggishness, unusually dry mouth or eyes, weakness); symptoms of kidney problems (eg, decreased urination; swelling of the ankles, feet, or legs); wheezing.
For Healthcare Professionals
Applies to sodium biphosphate / sodium phosphate: oral solution, oral tablet, rectal enema
Gastrointestinal side effects associated with sodium biphosphate-sodium phosphate tablets have included bloating (up to 47%), nausea (up to 37%), abdominal pain (up to 30%), and vomiting (up to 10%). Anal irritation, diarrhea, nausea, and stomach cramps have been reported with the enema formulation. Possible side effects associated with the enema formulation have included vomiting, abdominal pain, abdominal distension, gastrointestinal pain, and anal discomfort.
Metabolic side effects associated with sodium biphosphate-sodium phosphate tablets have included changes in serum electrolytes (including phosphate, calcium, potassium, and sodium). Possible side effects associated with the enema formulation have included dehydration, hyperphosphatemia, hypocalcemia, hypernatremia, and metabolic acidosis.
Renal side effects associated with sodium biphosphate-sodium phosphate tablets have included renal impairment, increased blood urea nitrogen (BUN), increased creatinine, acute renal failure, acute phosphate nephropathy, nephrocalcinosis, and renal tubular necrosis during postmarketing experience.
Nervous system side effects have included dizziness and headache. Seizures have been reported during postmarketing experience.
Cardiovascular side effects associated with sodium biphosphate-sodium phosphate tablets have included arrhythmias during postmarketing experience.
Hypersensitivity side effects associated with sodium biphosphate-sodium phosphate tablets have included anaphylaxis, rash, pruritus, urticaria, throat tightness, bronchospasm, dyspnea, pharyngeal edema, dysphasia, paresthesia, swelling of the lips and tongue, and facial swelling during postmarketing experience. Possible side effects associated with the enema formulation have included hypersensitivity and pruritus.
Respiratory side effects associated with sodium biphosphate-sodium phosphate tablets have included bronchospasm, dyspnea, and dysphagia during postmarketing experience; these side effects were associated with hypersensitivity reactions.
Other possible side effects associated with the enema formulation have included chills, blistering, and stinging.
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