Penetrex Side Effects

Generic Name: enoxacin

Note: This page contains side effects data for the generic drug enoxacin. It is possible that some of the dosage forms included below may not apply to the brand name Penetrex.

It is possible that some side effects of Penetrex may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to enoxacin: oral tablet

If you experience any of the following serious side effects, stop taking enoxacin (the active ingredient contained in Penetrex) and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

  • seizures;

  • confusion or hallucinations;

  • liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or

  • muscle or joint pain.

If you experience any of the following less serious side effects, continue taking enoxacin and talk to your doctor:

  • nausea, vomiting, or diarrhea;

  • headache, lightheadedness, or drowsiness;

  • ringing in your ears; or

  • increased sensitivity of the skin to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

For Healthcare Professionals

Applies to enoxacin: oral tablet

General

Enoxacin (the active ingredient contained in Penetrex) therapy is generally well tolerated, and adverse effects are mild in nature. Discontinuation of therapy due to adverse effects occurs in approximately 3% of patients.

Gastrointestinal

Gastrointestinal disturbances due to enoxacin (the active ingredient contained in Penetrex) therapy may occur in up to 9% of patients. This most frequently includes nausea, abdominal pain, anorexia, dyspepsia, and diarrhea. Enoxacin therapy has resulted in pseudomembranous colitis although it has minimal effect on the anaerobic flora of the GI tract.

Nervous system

Nervous system adverse effects occur in approximately 2% to 3% of patients. These most commonly include headache, dizziness, fatigue, nervousness, agitation, and insomnia. Seizures have also been reported in susceptible patients.

Hypersensitivity

Hypersensitivity reactions resulting in rash and pruritus have been reported in up to 1% of patients treated with enoxacin (the active ingredient contained in Penetrex) Photosensitivity can occur. Erythema multiforme, toxic epidermal necrolysis, and Stevens-Johnson Syndrome have also been reported.

Hepatic

Asymptomatic elevations in hepatic transaminases have been reported in less than 1% of patients treated with enoxacin (the active ingredient contained in Penetrex) Cholestatic jaundice has been reported in one patient shortly after enoxacin administration.

Hematologic

Hematologic abnormalities such as eosinophilia and leukopenia occur in less than 1% of enoxacin-treated patients.

Musculoskeletal

Arthralgias and myalgias occur rarely.

Cardiovascular

Tachycardia and facial flushing have been reported rarely.

Other

Women treated with enoxacin (the active ingredient contained in Penetrex) may experience vaginal pruritus and vaginitis.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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