Paromycin Side Effects
Generic Name: paromomycin
Note: This page contains side effects data for the generic drug paromomycin. It is possible that some of the dosage forms included below may not apply to the brand name Paromycin.
It is possible that some side effects of Paromycin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to paromomycin: oral capsule
As well as its needed effects, paromomycin (the active ingredient contained in Paromycin) may cause unwanted side effects that require medical attention.
Some paromomycin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:Incidence not known
- Abdominal or stomach cramps
For Healthcare Professionals
Applies to paromomycin: oral capsule
Gastrointestinal side effects of paromomycin (the active ingredient contained in Paromycin) have commonly included nausea, vomiting, diarrhea, and abdominal discomfort, especially with doses greater than 3 g per day. Malabsorption of xylose and sucrose has been reported. A case of pancreatitis in an AIDS patient has been attributed to paromomycin.
A patient with AIDS developed pancreatitis after five days of therapy with paromomycin for cryptosporidiosis. Serum amylase declined progressively after paromomycin was discontinued, but became elevated after reinstitution of therapy.
Nervous system side effects have rarely included ototoxicity and sensorineural damage, usually in patients who also had hepatic disease. Rarely, patients may also experience headache or vertigo.
Nephrotoxicity is a consideration with the use of any aminoglycoside, however, paromomycin (the active ingredient contained in Paromycin) is poorly absorbed by the gastrointestinal tract. Accumulation of paromomycin may be problematic in patients with impaired renal function and patients treated with multiple or prolonged courses of therapy.
Hepatic side effects have included transient elevated aspartate transaminase (greater than 3 times ULN) and alanine transaminase (greater than 3 times ULN) in patients receiving intramuscular paromomycin (the active ingredient contained in Paromycin) during a clinical study.
Local side effects have included injection site pain and swelling in patients receiving intramuscular paromomycin (the active ingredient contained in Paromycin) during a clinical study.
Other side effects have included pyrexia in patients receiving intramuscular paromomycin (the active ingredient contained in Paromycin) during a clinical study.
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