Panhematin Side Effects

Generic name: hemin

Medically reviewed by Drugs.com. Last updated on Apr 24, 2023.

Note: This document contains side effect information about hemin. Some dosage forms listed on this page may not apply to the brand name Panhematin.

Applies to hemin: intravenous powder for solution.

Serious side effects of Panhematin

Along with its needed effects, hemin (the active ingredient contained in Panhematin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking hemin:

Less common

Bluish color
changes in skin color
fever
itching, pain, redness, swelling, tenderness, or warmth on the skin
redness or pain at the catheter site
swelling of the foot or leg tenderness

Incidence not known

Back pain
black, tarry stools
bleeding gums
blood in the urine or stools
dark urine
decreased urination
dizziness
fainting
fever
irregular heartbeat
lightheadedness
pinpoint red spots on the skin
stomach pain
tiredness
unusual bleeding or bruising
yellow eyes or skin

Other side effects of Panhematin

Some side effects of hemin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

Less common

Rash

Incidence not known

Dry, red, hot, or irritated skin

For Healthcare Professionals

Applies to hemin: intravenous powder for injection.

Hematologic

Very common (10% or more): Poor venous access

Postmarketing reports: Thrombocytopenia, coagulopathy (including prolonged prothrombin time and prolonged partial thromboplastin time), hemolysis^[Ref]

Hypersensitivity

Rare (0.01% to 0.1%): Anaphylactoid reaction, hypersensitivity (e.g., dermatitis medicamentosa, tongue edema)^[Ref]

Immunologic

Common (1% to 10%): Cellulitis^[Ref]

Local

Common (1% to 10%): Phlebitis/injection site phlebitis, catheter-related complication (e.g., erythema, pain, bleeding, extravasation, infusion site swelling)^[Ref]

Metabolic

Uncommon (0.1% to 1%): Increased serum ferritin

Frequency not reported: Blood creatinine increased

Postmarketing reports: Iron overload^[Ref]

Renal

Postmarketing reports: Reversible renal shutdown (after administration of excessive doses)^[Ref]

Cardiovascular

Frequency not reported: Phlebitis (with or without leukocytosis and with or without mild pyrexia has occurred after administration of this drug through small arm veins)^[Ref]