Orphenadrine Side Effects

Brand Names: Antiflex, Norflex

Please note - some side effects for Orphenadrine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Orphenadrine - for the Consumer

Orphenadrine

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Orphenadrine:

Blurred vision; constipation; dizziness or lightheadedness; drowsiness; dry mouth; headache; nausea; stomach irritation or upset; vomiting; weakness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation, chills, fever, or sore throat; confusion; fainting; fast or irregular heartbeat; hallucinations; pain, swelling, or redness the injection site; severe or persistent tiredness or weakness; tremor; trouble urinating or inability to urinate; unusual bruising or bleeding; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Orphenadrine/Aspirin/Caffeine

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Orphenadrine/Aspirin/Caffeine:

Blurred vision; constipation; dizziness; drowsiness; dry mouth; headache; heartburn; irritability; nausea; nervousness; upset stomach; vomiting; weakness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; confusion; decreased urination; diarrhea; fainting; fast or irregular heartbeat; hallucinations; hearing loss; ringing in the ears; severe or persistent dizziness or drowsiness; severe or persistent stomach pain or heartburn; shakiness; trouble sleeping; vision changes; vomit that looks like blood or coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Orphenadrine Extended-Release Tablets

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Orphenadrine Extended-Release Tablets:

Blurred vision; constipation; dizziness or lightheadedness; drowsiness; dry mouth; headache; nausea; stomach irritation or upset; vomiting; weakness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; chills, fever, or sore throat; confusion; fainting; fast or irregular heartbeat; hallucinations; severe or persistent tiredness or weakness; tremor; trouble urinating or inability to urinate; unusual bruising or bleeding; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Side Effects by Body System - for Healthcare Professionals

Nervous system

Nervous system side effects have included headache, light-headedness, dizziness, drowsiness, syncope and tremor. Infrequently, elderly patients have experienced mental confusion.

Ocular

Ocular side effects have included blurred vision, dilatation of pupils, and increased ocular tension.

Cardiovascular

Cardiovascular side effects have included tachycardia and palpitations.

Genitourinary

Genitourinary side effects have included urinary hesitancy and retention.

Gastrointestinal

Gastrointestinal side effects have included dry mouth, nausea, vomiting, and gastric irritation.

Musculoskeletal

Musculoskeletal side effects have included weakness.

Dermatologic

Dermatologic side effects have included pruritus, and rarely, urticaria and other dermatosis.

Psychiatric

Psychiatric side effects have included hallucinations and agitation.

Hematologic

Hematologic side effects have included very rare cases of aplastic anemia, however, no causal relationship has been established.

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