Onglyza Side Effects
Generic Name: saxagliptin
Note: This document contains side effect information about saxagliptin. Some of the dosage forms listed on this page may not apply to the brand name Onglyza.
Some side effects of Onglyza may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to saxagliptin: oral tablet
Along with its needed effects, saxagliptin (the active ingredient contained in Onglyza) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking saxagliptin:More common
- bladder pain
- bloating or swelling of the face, arms, hands, lower legs, or feet
- bloody or cloudy urine
- blurred vision
- body aches or pain
- cold sweats
- cool, pale skin
- difficult, burning, or painful urination
- difficulty with breathing
- ear congestion
- fast heartbeat
- frequent urge to urinate
- increased hunger
- loss of voice
- lower back or side pain
- nasal congestion
- rapid weight gain
- runny nose
- slurred speech
- sore throat
- tingling of the hands or feet
- unusual tiredness or weakness
- unusual weight gain or loss
- darkened urine
- difficulty with swallowing
- flaking or peeling of the skin
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- loss of appetite
- pains in the stomach, side, or abdomen, possibly radiating to the back
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- shortness of breath
- skin rash
- tightness in the chest
- yellow eyes or skin
Some side effects of saxagliptin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common
- pain or tenderness around the eyes and cheekbones
- redness of the skin
For Healthcare Professionals
Applies to saxagliptin: oral tablet
Endocrine side effects have included hypoglycemia.
Nervous system side effects have included headache.
Respiratory side effects have included upper respiratory tract infection, sinusitis, and nasopharyngitis.
Gastrointestinal side effects have included abdominal pain, gastroenteritis, and vomiting. Postmarketing side effects include acute pancreatitis.
Hematologic side effects include a dose-related mean decrease in absolute lymphocyte count not associated with clinically relevant adverse reactions.
Hypersensitivity side effects have included urticaria and facial edema. Postmarketing hypersensitivity reactions of anaphylaxis, angioedema, and exfoliative skin conditions have been reported.
Cardiovascular side effects have included peripheral edema.
More about Onglyza (saxagliptin)
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