Nyamyc Side Effects

Generic name: nystatin topical

Note: This document contains side effect information about nystatin topical. Some of the dosage forms listed on this page may not apply to the brand name Nyamyc.

Some side effects of Nyamyc may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to nystatin topical: vaginal tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking nystatin topical (the active ingredient contained in Nyamyc) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include mild burning, itching, or irritation, and an increased need to urinate.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to nystatin topical: topical cream, topical kit, topical ointment, topical powder, vaginal tablet

Dermatologic

Dermatologic side effects associated with nystatin topical (the active ingredient contained in Nyamyc) powder, cream, and ointment have included skin irritation, burning, itching, rash, eczema, and pain on application in less than 0.1% of patients.

Genitourinary

Genitourinary side effects associated with nystatin vaginal tablets have included vaginal irritation, burning, and itching. At least one case of severe vulvovaginitis has also been reported.

A 64-year-old female experienced severe vulvovaginitis while receiving intravaginal nystatin therapy for Candida glabrata infection. She was administered nystatin vaginal tablets, 100,000 units twice daily for 14 days. She returned immediately after having completed the course complaining of intense skin rash in the vulvar area accompanied by severe irritation, burning, and itching. Therapy with a hydrocortisone cream and intramuscular betamethasone dipropionate was initiated. A week later, she had marked improvement with clearing of the vulvovaginal erythema and edema.

Hypersensitivity

Hypersensitivity side effects associated with nystatin topical (the active ingredient contained in Nyamyc) powder, cream, and ointment have included allergic reactions and allergic contact dermatitis in less than 0.1% of patients. Stevens-Johnson syndrome has also been reported.

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