Nuromax Side Effects
Please note - some side effects for Nuromax may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
Nuromax Side Effects - for the Professional
Applies to: intravenous injection
The most frequent adverse effect of nondepolarizing blocking agents as a class consists of an extension of the pharmacological action beyond the time needed for surgery and anesthesia. This effect may vary from skeletal muscle weakness to profound and prolonged skeletal muscle paralysis resulting in respiratory insufficiency and apnea which require manual or mechanical ventilation until recovery is judged to be clinically adequate. Inadequate reversal of neuromuscular block from Nuromax is possible, as with all nondepolarizing agents. Prolonged neuromuscular block and inadequate reversal may lead to postoperative complications.
Observed in Clinical Trials
Adverse experiences were uncommon among the 1034 surgical patients and volunteers who received Nuromax and other drugs in US clinical studies in the course of a wide variety of procedures conducted during balanced or inhalational anesthesia. The following adverse experiences were reported in patients administered Nuromax (all events judged by investigators during the clinical trials to have a possible causal relationship):
|Cardiovascular:*||Hypotension,† flushing,† ventricular fibrillation, myocardial infarction|
* Reports of ventricular fibrillation (n = 1) and myocardial infarction (n = 1) were limited to ASA Class 3-4 patients undergoing cardiac surgery (n = 142).
† 0.3% incidence. All other reactions unmarked were ≤ 0.1%.
|Dermatological:||Urticaria, injection site reaction|
|Nonspecific:||Difficult neuromuscular block reversal, prolonged drug effect, fever|
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