Nitric oxide Side Effects

Brand Names: Inomax

Please note - some side effects for Nitric oxide may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects by Body System

Hematologic

Hematologic side effects including methemoglobinemia (which increases with the dose of nitric oxide) have been reported. Elevated NO2 levels have also been reported.

In one study 35% of neonates treated with nitrous oxide 80 ppm had methemoglobin levels exceeding 7%. Following discontinuation or reduction of nitric oxide the methemoglobin levels returned to baseline over a period of hours.

Cardiovascular

Cardiovascular side effects including hypotension (13%) have been reported.

Other

Other side effects including withdrawal (12%), sepsis (7%), infection (6%), and cellulitis (5%) have been reported. Headaches have been associated with environmental exposure of nitric oxide by hospital staff.

Respiratory

Respiratory side effects including atelectasis (9%) and stridor (5%) have been reported.

Renal

Renal side effects including hematuria (8%) have been reported.

Metabolic

Metabolic side effects including hyperglycemia (8%) have been reported.

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