Niacinamide Side Effects
Some side effects of niacinamide may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to niacinamide: tablets
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking niacinamide:
Diarrhea; dizziness; headache; itching; nausea; stomach upset; temporary feeling of warmth or flushing of the skin.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; changes in vision; dark urine; decreased urination; fast or irregular heartbeat; loss of appetite; muscle pain or weakness; numbness or persistent tingling of the skin; persistent nausea, vomiting, or general "unwell" feeling; severe or prolonged flushing of the skin; stomach pain; swelling of the hands, legs, or feet; vomit that looks like coffee grounds; yellowing of the skin or eyes.
For Healthcare Professionals
Applies to niacinamide: compounding powder, oral tablet
Cardiovascular side effects are rare and mild and have included tachycardia.
Metabolic side effects have included hyperglycemia and hyperuricemia.
Nervous system side effects have included headache.
Gastrointestinal side effects have included bloating, flatulence, diarrhea, stomach upset, and nausea.
Dermatologic side effects have included increased sebaceous gland activity, dry skin, itching, and rash.
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