Nesiritide Side Effects

Medically reviewed by Drugs.com. Last updated on Jul 7, 2023.

Applies to nesiritide: intravenous powder for injection.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have:

• a light-headed feeling, like you might pass out; or

• little or no urination.

Common side effects may include:

• dizziness;

• nausea;

• headache; or

• back pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to nesiritide: intravenous powder for injection.

General

The most frequently reported side effects were hypotension, headache, nausea, renal impairment, and back pain.^[Ref]

Cardiovascular

Very common (10% or more): Hypotension (12%)^[Ref]

Renal

Very common (10% or more): GFR decreased (up to 31.4%), serum creatinine increased (up to 28%)^[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness^[Ref]

Dermatologic

Postmarketing reports: Pruritus, rash^[Ref]

Musculoskeletal

Common (1% to 10%): Back pain^[Ref]

Metabolic

Common (1% to 10%): Hypoglycemia^[Ref]

Gastrointestinal

Common (1% to 10%): Nausea^[Ref]

Local

Postmarketing reports: Infusion site extravasation^[Ref]

Hypersensitivity

Postmarketing reports: Hypersensitivity reaction^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer