Nasarel Side Effects

Generic name: flunisolide nasal

Note: This document contains side effect information about flunisolide nasal. Some of the dosage forms listed on this page may not apply to the brand name Nasarel.

Some side effects of Nasarel may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to flunisolide nasal: nasal spray

Get emergency medical help if you have any of these signs of an allergic reaction while taking flunisolide nasal (the active ingredient contained in Nasarel) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• severe or ongoing nose bleed;

• sores in the nose that won't heal; or

• weakness, tired feeling, nausea, loss of appetite, weight loss.

Less serious side effects of flunisolide nasal may include:

• burning or stinging in your nose;

• changes in your sense of smell;

• minor nosebleed;

• unusual taste after using the spray;

• dry nose, cough, sore throat; or

• hoarse voice.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to flunisolide nasal: nasal spray

General

Flunisolide has been generally well tolerated and, due to its route of administration, has not been inclined to produce the adverse effects generally associated with systemic corticosteroids. The most frequent complaints have been related to nasal mucus membrane irritation.

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting in less than 5% of patients. Bitterness and/or bad taste occurred more frequently.

Respiratory

Respiratory side effects have included nasal irritation, burning and stinging, congestion, epistaxis, sneezing, and rarely, nasal septal perforations. Temporary or permanent loss of the sense of smell and taste have occurred with both oral inhalation and intranasal formulations.

Nervous system

Nervous system side effects have been generally limited to headache, which occurred in less than 5% of patients.

Endocrine

Endocrine side effects have rarely included suppression of the hypothalamic-pituitary-adrenal axis. The risk of adrenal suppression has been less than that associated with systemic corticosteroids and was generally only of concern when using higher than recommended dosages or in patients who may be particularly sensitive.

Dermatologic

Dermatologic side effects have included rare reports of rash.

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