Motofen Side Effects
Generic Name: atropine / difenoxin
Note: This document contains side effect information about atropine / difenoxin. Some of the dosage forms listed on this page may not apply to the brand name Motofen.
Some side effects of Motofen may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to atropine / difenoxin: oral tablet
Along with its needed effects, atropine / difenoxin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking atropine / difenoxin:
- loss of appetite
- stomach pain (severe) with nausea and vomiting
Get emergency help immediately if any of the following symptoms of overdose occur while taking atropine / difenoxin:
- Blurred vision (continuing) or changes in near vision
- drowsiness (severe)
- dryness of mouth, nose, and throat (severe)
- fast heartbeat
- shortness of breath or troubled breathing (severe)
- unusual excitement, nervousness, restlessness, or irritability
- unusual warmth, dryness, and flushing of skin
Some side effects of atropine / difenoxin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common or rare
- Blurred vision
- difficult urination
- dizziness or lightheadedness
- dryness of skin and mouth
- trouble in sleeping
- unusual tiredness or weakness
After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:
- Increased sweating
- muscle cramps
- nausea or vomiting
- shivering or trembling
- stomach cramps
For Healthcare Professionals
Applies to atropine / difenoxin: oral tablet
Gastrointestinal side effects have included nausea (1 in 15 patients), vomiting (1 in 30 patients), dry mouth (1 in 30 patients), epigastric distress (1 in 100 patients), and constipation ( 1 in 300 patients).
In patients receiving chemically-related drugs, toxic megacolon, paralytic ileus, pancreatitis, and anorexia have been reported.
Cardiovascular side effects have included tachycardia with the use of atropine.
Nervous system side effects have included dizziness (1 in 20 patients), lightheadedness (1 in 20 patients), drowsiness (1 in 25 patients), headache (1 in 40 patients). Other less common side effects have included tiredness and insomnia.
Patients receiving chemically-related drugs have reported confusion, numbness of extremities, euphoria, depression, and sedation.
Hypersensitivity side effects have included anaphylaxis, angioneurotic edema, urticaria, swelling of the gums, and pruritus.
Ocular side effects have included burning eyes and blurred vision.
General side effects reported with use of atropine have included flushing and hyperthermia.
Genitourinary side effects have included urinary retention with use of atropine.
More about Motofen (atropine / difenoxin)
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