Morphine Sulfate Solution, Concentrate Side Effects
Please note - some side effects for Morphine Sulfate Solution, Concentrate may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
Morphine Sulfate Solution, Concentrate Side Effects - for the Professional
Morphine Sulfate Solution, Concentrate
THE MAJOR HAZARDS OF MORPHINE, AS OF OTHER NARCOTIC ANALGESICS, ARE RESPIRATORY DEPRESSION AND, TO A LESSER DEGREE, CIRCULATORY DEPRESSION, RESPIRATORY ARREST, SHOCK, AND CARDIAC ARREST HAVE OCCURRED.
The most frequently observed adverse reactions include lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. These effects seem to be more prominent in ambulatory patients and in those who are suffering severe pain. In such individuals, lower doses are advisable. Some adverse reactions may be alleviated in the ambulatory patient if he lies down.
Other adverse reactions include the following; Central Nervous System - Euphoria, dysphoria, weakness, headache, insomnia, agitation, disorientation, and visual disturbances.
Gastrointestinal - Dry mouth, anorexia, constipation, and biliary tract spasm.
Cardiovascular - Flushing of the face, bradycardia, palpitation, faintness and syncope.
Allergic - Pruritus, urticaria, other skin rashes, edema, and, rarely hemorrhagic urticaria.
Treatment of the most frequent adverse reactionsConstipation
Ample intake of water or other liquids should be encouraged. Concomitant administration of a stool softener and peristaltic stimulant with the narcotic analgesic can be an effective preventive measure for those patients in need of therapeutics. If elimination does not occur for two days, an enema should be administered to prevent impaction.
In the event diarrhea occurs, seepage around fecal impaction is a possible cause to consider before antidiarrheal measures are employed.Nausea and Vomiting
Phenothiazines and antihistamines can be effective treatments of nausea of the medullary and vestibular sources respectively. However, these drugs may potentiate the side effects of the narcotic or the anti-nauseant.Drowsiness (sedation)
Once pain control is achieved, undersirable sedation can be minimized by titrating the dosage to a level that just maintains a tolerable pain or pain free state.Top
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