Mintezol Side Effects

Generic Name: thiabendazole

Please note - some side effects for Mintezol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Mintezol - for the Consumer

Mintezol

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Mintezol:

Appetite loss; bad urine odor; diarrhea; dizziness; drowsiness; dry eyes; giddiness; headache; indigestion; irritability; nausea; sensation of floating; stomach upset or pain; tiredness; vomiting; weakness; worms in mouth or nose.

Seek medical attention right away if any of these SEVERE side effects occur when using Mintezol:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; blurred vision; change in vision; chills; collapse; confusion; dark urine; depression; enlarged lymph nodes; flushing; hoarseness; increased thirst or urination; loss of coordination; numbness; red, swollen, or blistered skin; ringing in the ears; seizures; severe stomach pain; sore throat or fever; strange feeling in your eyes; uncontrolled urination; vision tinged yellow; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Mintezol Suspension

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Mintezol Suspension:

Appetite loss; bad urine odor; diarrhea; dizziness; drowsiness; dry eyes; giddiness; headache; indigestion; irritability; nausea; sensation of floating; stomach upset or pain; tiredness; vomiting; weakness; worms in mouth or nose.

Seek medical attention right away if any of these SEVERE side effects occur when using Mintezol Suspension:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; blurred vision; change in vision; chills; collapse; confusion; dark urine; depression; enlarged lymph nodes; flushing; hoarseness; increased thirst or urination; loss of coordination; numbness; red, swollen, or blistered skin; ringing in the ears; seizures; severe stomach pain; sore throat or fever; strange feeling in your eyes; uncontrolled urination; vision tinged yellow; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

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Mintezol Side Effects - for the Professional

Mintezol

Gastrointestinal: anorexia, nausea, vomiting, diarrhea, epigastric distress, abdominal pain, jaundice, cholestasis, parenchymal liver damage and hepatic failure.

Central Nervous System: dizziness, weariness, drowsiness, giddiness, headache, numbness, hyperirritability, convulsions, collapse, confusion, depression, floating sensation, weakness and lack of coordination.

Special Senses: tinnitus, abnormal sensation in eyes, xanthopsia, blurred vision, reduced vision, drying of mucous membranes (mouth, eyes, etc.), Sicca syndrome.

Cardiovascular: hypotension.

Metabolic: hyperglycemia.

Hematologic: transient leukopenia.

Genitourinary: hematuria, enuresis, malodor of the urine, crystalluria.

Hypersensitivity: pruritus, fever, facial flush, chills, conjunctival injection, angioedema, anaphylaxis, skin rashes (including perianal), erythema multiforme (including Stevens-Johnson syndrome), and lymphadenopathy.

Miscellaneous: appearance of live Ascaris in the mouth and nose.

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Side Effects by Body System - for Healthcare Professionals

Gastrointestinal

Gastrointestinal side effects have commonly included nausea, vomiting, anorexia, and abdominal pain. These side effects generally only last 1 to 2 days and do not require drug discontinuation. Epigastric distress and abdominal pain have also been reported.

Nervous system

Nervous system side effects have included drowsiness, dizziness, giddiness, headache, paresthesias, weariness, numbness, hyperirritability, convulsions, collapse, confusion, depression, floating sensation, weakness, and lack of coordination.

Hypersensitivity

Erythema multiforme (including Stevens-Johnson syndrome) and toxic epidermal necrolysis generally do not occur for several weeks after thiabendazole is discontinued. The reaction generally starts with a skin eruption which quickly progresses. Two reported cases had complete recovery after several weeks of therapy.

Hypersensitivity adverse effects have included pruritic rash reactions, fever, facial flush, chills, conjunctival injection, angioedema, anaphylaxis, skin rashes (including perianal), erythema multiforme (including Stevens-Johnson syndrome), toxic epidermal necrolysis, and lymphadenopathy.

Hepatic

Sicca complex has been frequently noted with the hepatic changes associated with thiabendazole. This clinical picture includes keratoconjunctivitis sicca and xerostomia. This also appears to be reversible in most cases without medical intervention.

Hepatic side effects reported have included liver damage. It may manifest as jaundice, cholestasis, sicca syndrome, malaise, light-colored stools, and gastrointestinal upset. These symptoms generally do not occur for several weeks following thiabendazole therapy completion. Therapy usually consists of only supportive measures. In most cases the hepatic damage is reversible, although at least one patient has died as a result of hepatic damage. Sicca complex has also been reported.

Ocular

Ocular side effects have included abnormal sensation in eyes, xanthopsia, blurred vision, and transient disturbances in vision.

Cardiovascular

Cardiovascular side effects have included hypotension.

Metabolic

Metabolic side effects have included hyperglycemia.

Hematologic

Hematologic side effects have included transient leukopenia.

Genitourinary

Genitourinary side effects have included hematuria, enuresis, malodor of the urine, and crystalluria.

Psychiatric

Psychiatric side effects have included psychic alterations.

Other

Other side effects have included tinnitus, drying of mucous membranes, and live Ascaris in the mouth and nose.

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