Metaxalone Side Effects

Brand Names: Skelaxin

Please note - some side effects for Metaxalone may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Metaxalone - for the Consumer

Metaxalone

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Metaxalone:

Dizziness; drowsiness; headache; irritability; nausea; nervousness; upset stomach; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever, chills, or sore throat; unusual or severe tiredness or weakness; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Metaxalone Side Effects - for the Professional

Metaxalone

The most frequent reactions to Metaxalone include:

CNS: drowsiness, dizziness, headache and nervousness or “irritability”;

Digestive: nausea, vomiting, gastrointestinal upset.

Other adverse reactions are:

Immune System: hypersensitivity reaction, rash with or without pruritus;

Hematologic: leukopenia, hemolytic anemia;

Hepatobiliary: jaundice.

Though rare, anaphylactoid reactions have been reported with Metaxalone.

Side Effects by Body System - for Healthcare Professionals

Gastrointestinal

Gastrointestinal side effects including nausea, vomiting, and gastrointestinal upset have been reported.

Nervous system

Nervous system side effects including drowsiness, dizziness, headache, and nervousness or irritability have been reported.

Hematologic

Hematologic side effects including leukopenia and hemolytic anemia have been reported.

Hypersensitivity

Hypersensitivity side effects including a hypersensitivity reaction characterized by a light rash with or without pruritus have been reported.

Hepatic

Hepatic side effects including elevation in cephalin flocculation tests (without concurrent changes in other liver function parameters) and jaundice have been reported.

Other

Other side effects including a false-positive Benedict's tests (due to an unknown reducing substance) have been reported.

A glucose-specific test may be used to differentiate findings.

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