Meperidine Injection Side Effects

Please note - some side effects for Meperidine Injection may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Meperidine Injection Side Effects - for the Professional

Meperidine Injection

The major hazards of meperidine, as with other narcotic analgesics, are respiratory depression and, to a lesser degree, circulatory depression; respiratory arrest, shock and cardiac arrest have occurred.

The most frequently observed adverse reactions include lightheadedness, dizziness, sedation, nausea, vomiting and sweating. These effects seem to be more prominent in ambulatory patients and in those who are not experiencing severe pain. In such individuals, lower doses are advisable. Some adverse reactions in ambulatory patients may be alleviated if the patient lies down. Other adverse reactions include:

Central Nervous System-Euphoria, dysphoria, weakness, headache, agitation, tremor, uncoordinated muscle movements, severe convulsions, transient hallucinations and disorientation, visual disturbances. Inadvertent injection about a nerve trunk may result in sensory-motor paralysis which is usually, though not always, transitory.

Gastrointestinal-Dry mouth, constipation, biliary tract spasm.

Cardiovascular-Flushing of the face, tachycardia, bradycardia, palpitations, hypotension, syncope, phlebitis following intravenous injection.

Genitourinary-Urinary retention.

Allergic-Pruritus, urticaria, other skin rashes, wheal and flare over the vein with IV injection.

Other-Pain at injection site; local tissue irritation and induration following subcutaneous injection, particularly when repeated; antidiuretic effect.

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