Meclofenamate Side Effects

Some side effects of meclofenamate may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to meclofenamate: oral capsules

Side effects include:

Diarrhea, nausea with or without vomiting, other GI disorders, abdominal pain, flatulence, pyrosis, dizziness, headache, rash.

For Healthcare Professionals

Applies to meclofenamate: compounding powder, oral capsule

Cardiovascular

Cardiovascular side effects have included edema and palpitations.

Dermatologic

Dermatologic side effects have included rash, urticaria, and pruritus. Dermatologic side effects reported in less than 1% of test subjects have included erythema multiforme, Stevens-Johnson Syndrome, and exfoliative dermatitis.

Gastrointestinal

Gastrointestinal side effects have included diarrhea (10 to 33%), nausea with or without vomiting (11%), other gastrointestinal disorders (10%), and abdominal pain. Less frequently reported gastrointestinal side effects have included pyrosis, flatulence, anorexia, constipation, stomatitis, and peptic ulcer (most patients with peptic ulcer had either a history of ulcer disease or were receiving concomitant anti-inflammatory drugs). Gastrointestinal side effects reported in less than 1% of patients have included bleeding and/or perforation with or without obvious ulcer formation, colitis, cholestatic jaundice, and gastric ileus.

General

General side effects with an unknown causal relationship have included malaise, fatigue, paresthesia, insomnia, depression, blurred vision, taste disturbances, decreased visual acuity, temporary loss of vision, reversible loss of color vision, retinal changes including macular fibrosis, macular and perimacular edema, conjunctivitis, and iritis.

Hematologic

Hematologic side effects were reported in less than 1% of test subjects and have included neutropenia, thrombocytopenic purpura, leukopenia, agranulocytosis, hemolytic anemia, eosinophilia, and decrease in hemoglobin and/or hematocrit.

Hepatic

Hepatic side effects have included alteration of lever function tests (less than 1%).

Nervous system

Nervous system side effects have included headache and dizziness.

Other

Other side effects have included tinnitus (3 to 9%). Other side effects occurring in less than 1% of test subjects have included lupus and serum sickness-like symptoms.

Renal

Renal side effects have included renal failure (less than 1%) and nocturia (less than 1%).

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Got questions about Rheumatoid Arthritis? Get answers from our expert Dr. Carteron. Click Here

Close
Hide
(web3)