Mebaral Side Effects

Generic name: mephobarbital

Note: This document contains side effect information about mephobarbital. Some of the dosage forms listed on this page may not apply to the brand name Mebaral.

Some side effects of Mebaral may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to mephobarbital: oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking mephobarbital (the active ingredient contained in Mebaral) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• confusion, hallucinations;

• slow heart rate; or

• feeling like you might pass out.

Less serious side effects of mephobarbital may include:

• dizziness;

• memory or thinking problems;

• feeling nervous or agitated;

• nausea, vomiting; or

• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to mephobarbital: oral tablet

Nervous system

Nervous system side effects including primarily somnolence (1% to 3%) have been reported. Agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucination, insomnia, anxiety, dizziness, and abnormal thinking have all been reported to occur in less than 1% of treated patients. Headache has been reported with chronic use.

Respiratory

Respiratory side effects including hypoventilation and apnea have been reported to occur in less than 1% of treated patients.

Cardiovascular

Cardiovascular side effects including bradycardia, hypotension, and syncope have been reported to occur in less than 1% of treated patients.

Gastrointestinal

Gastrointestinal side effects including nausea, vomiting, and constipation have been reported to occur in less than 1% of treated patients.

Hypersensitivity

Hypersensitivity side effects including angioedema, skin rashes, and exfoliative dermatitis have been reported to occur with chronic use in less than 1% of treated patients.

General

General side effects including fever have been reported to occur with chronic use in less than 1% of treated patients.

Hepatic

Hepatic side effects including liver damage have been reported to occur with chronic use in less than 1% of treated patients.

Hematologic

Hematologic side effects including megaloblastic anemia have been reported to occur with chronic use in less than 1% of treated patients.

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