Maxair Autohaler Side Effects

Generic name: pirbuterol

Note: This document contains side effect information about pirbuterol. Some of the dosage forms listed on this page may not apply to the brand name Maxair Autohaler.

Some side effects of Maxair Autohaler may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to pirbuterol: inhalation aerosol

Get emergency medical help if you have any of these signs of an allergic reaction while taking pirbuterol (the active ingredient contained in Maxair Autohaler) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• bronchospasm (wheezing, chest tightness, trouble breathing), especially after starting a new canister of this medicine;

• chest pain and fast, pounding, or uneven heart beats;

• tremor, nervousness;

• low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or

• dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects of pirbuterol may include:

• headache, dizziness;

• sleep problems (insomnia);

• cough, hoarseness, sore throat, runny or stuffy nose;

• mild nausea, vomiting;

• dry mouth and throat;

• muscle pain; or

• diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to pirbuterol: inhalation aerosol

Cardiovascular

Cardiovascular side effects have included palpitations and peripheral vasodilation, commonly resulting in reflex tachycardia. Blood pressure may increase or decrease. Higher doses may rarely aggravate angina, myocardial ischemia, or cause atrial or ventricular arrhythmias.

Although most studies have not revealed a significant effect of pirbuterol on blood pressure or heart rate, anecdotally significant increases have been noted. Aggravation of angina may be due to tachycardia produced by pirbuterol. Supraventricular premature beats and ventricular tachycardia have also been reported. Higher doses of pirbuterol should be used with caution in patients with cardiac disease, arrhythmias, or hypertension. All of these effects are dose-related and lower doses may be tolerated.

Musculoskeletal

Musculoskeletal side effects have included tremors, especially at higher doses.

Gastrointestinal

Gastrointestinal side effects have included nausea, dry mouth, and diarrhea.

Metabolic

Metabolic side effects have included hypokalemia and, less commonly, hyperglycemia.

Nervous system

Nervous system side effects have included nervousness, dizziness, insomnia, and headache.

Respiratory

Respiratory side effects have included cough. Rare instances of paradoxical bronchoconstriction have been associated with the use of pirbuterol (the active ingredient contained in Maxair Autohaler)

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