Medication Guide App

Mafenide topical Side Effects

Not all side effects for mafenide topical may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to mafenide topical: topical cream, topical powder for solution, topical powder for suspension

In addition to its needed effects, some unwanted effects may be caused by mafenide topical. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking mafenide topical:

Less common
  • Itching
  • skin rash or redness
  • swelling of face or skin
  • wheezing or troubled breathing
Rare
  • Bleeding or oozing of skin
  • drowsiness
  • fast, deep breathing
  • nausea
Incidence unknown
  • Black, tarry stools
  • chest pain
  • chills
  • cough or hoarseness
  • dark urine
  • dizziness
  • fever
  • fluid-filled skin blisters
  • light-colored stools
  • lower back or side pain
  • numbness to feet, hands and around mouth
  • painful or difficult urination
  • rapid shallow breathing
  • sensitivity to the sun
  • shortness of breath
  • skin thinness
  • sore throat
  • sores, ulcers, or white spots on lips or in mouth
  • swollen glands
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • yellow eyes or skin

Some of the side effects that can occur with mafenide topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Pain or burning feeling on treated area(s)
Incidence unknown
  • Blisters
  • flushing
  • raised red swellings on the skin, lips, tongue, or in the throat
  • redness of skin
  • skin rash
  • softening of the skin
  • swelling
  • unusually warm skin

For Healthcare Professionals

Applies to mafenide topical: compounding powder, topical cream, topical powder for reconstitution

Dermatologic

Dermatologic side effects most frequently reported with the use of mafenide topical have included pain or burning on application. Excoriation of new skin and bleeding have rarely occurred.

Hypersensitivity

Hypersensitivity reactions have included rash, itching, facial edema, swelling, hives, blisters, erythema, and eosinophilia.

Respiratory

Respiratory side effects have included tachypnea or hyperventilation and decreases in pCO2.

Metabolic

Metabolic side effects have included acidosis and increases in serum chloride.

Gastrointestinal

Gastrointestinal side effects resulting from the accidental ingestion of mafenide topical have included diarrhea.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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