Mafenide topical Side Effects

Some side effects of mafenide topical may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to mafenide topical: topical cream, topical powder for reconstitution

Get emergency medical help if you have any of these signs of an allergic reaction while taking mafenide topical: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have a serious side effect such as:

• pale or yellowed skin, dark colored urine, fever, confusion or weakness;

• chest pain, fast or pounding heartbeats, headache, confusion;

• nausea, vomiting, stomach pain, appetite changes, muscle weakness, bone pain, and weight loss;

• rapid breathing, gasping, or feeling short of breath; or

• severe skin rash, bruising, severe tingling, numbness, or pain.

Less serious side effects of mafenide topical may include:

• mild skin rash, redness, or itching; or

• pain or burning of treated skin areas.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

For Healthcare Professionals

Applies to mafenide topical: compounding powder, topical cream, topical powder for reconstitution

Dermatologic

Dermatologic side effects most frequently reported with the use of mafenide topical have included pain or burning on application. Excoriation of new skin and bleeding have rarely occurred.

Hypersensitivity

Hypersensitivity reactions have included rash, itching, facial edema, swelling, hives, blisters, erythema, and eosinophilia.

Respiratory

Respiratory side effects have included tachypnea or hyperventilation and decreases in pCO2.

Metabolic

Metabolic side effects have included acidosis and increases in serum chloride.

Gastrointestinal

Gastrointestinal side effects resulting from the accidental ingestion of mafenide topical have included diarrhea.

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