Lodoxamide ophthalmic Side Effects

It is possible that some side effects of lodoxamide ophthalmic may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to lodoxamide ophthalmic: ophthalmic solution

Side Effects of This Medicine

Along with its needed effects, lodoxamide ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking lodoxamide ophthalmic:

Less common
  • Blurred vision
  • feeling of something in eye, itching, discomfort, redness, tearing or discharge, or other eye or eyelid irritation (not present before you started using this medicine or becoming worse while you are using this medicine)
  • Dizziness
  • mucus from eye, eye pain, or swelling of eye or eyelid (not present before you started using this medicine or becoming worse while you are using this medicine)
  • headache
  • sensitivity of eyes to light
  • skin rash

Some side effects of lodoxamide ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Burning or stinging (when medicine is applied)
Less common or rare
  • Aching eyes
  • crusting in corner of eye or on eyelid
  • drowsiness or sleepiness
  • dryness of nose or eyes
  • feeling of heat in eye
  • heat sensation on body
  • nausea or stomach discomfort
  • scales on eyelid or eyelash
  • sneezing
  • sticky feeling of eyes
  • tired eyes

For Healthcare Professionals

Applies to lodoxamide ophthalmic: ophthalmic solution


Ocular side effects have included burning, discomfort, or stinging upon instillation in 15% of patients. Ocular itching/pruritus, blurred vision, dry eye, tearing, discharge, hyperemia, crystalline deposits and foreign body sensation have been reported in 1% to 5% of patients. Corneal erosion, scales on eyelids or eyelashes, eye pain, eye edema, eye swelling, warm sensation in the eye, ocular fatigue, chemosis, corneal abrasion, keratopathy, keratitis, blepharitis, sticky sensation, epitheliopathy, anterior chamber cells, allergy, and blepharitis have been reported in less than 1% of patients.

Nervous system

Nervous system side effects have included headache (1.5%), and dizziness, somnolence, or heat sensation in less than 1% of patients.


Gastrointestinal side effects have included nausea and stomach discomfort in less than 1% of patients.


Respiratory side effects have included sneezing and dry nose in less than 1% of patients.


Dermatological side effects have included rash (<1%).

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