Linagliptin and metformin Side Effects

Please note - some side effects for Linagliptin and metformin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects by Body System - for Healthcare Professionals

Applies to: oral tablet

Respiratory

Respiratory side effects have included cough and nasopharyngitis.

Hypersensitivity

Hypersensitivity side effects have included urticaria, angioedema, bronchial hyperactivity, and localized skin exfoliation.

Musculoskeletal

Musculoskeletal side effects have included myalgia.

Gastrointestinal

Gastrointestinal side effects have included diarrhea, flatulence, indigestion, abdominal discomfort, decreased appetite, nausea, vomiting, and pancreatitis.

Nervous system

Nervous system side effects have included headache and asthenia.

Dermatologic

Dermatologic side effects have included pruritus.

Metabolic

Metabolic side effects of long-term treatment with metformin has been associated with a decrease in vitamin B12 absorption which may very rarely result in clinically significant vitamin B12 deficiency (e.g., megaloblastic anemia).

Endocrine

Endocrine side effects have included hypoglycemia.

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