Librax Side Effects

Please note - some side effects for Librax may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Librax - for the Consumer

Librax

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Librax:

Bloating; blurred vision; clumsiness; confusion; constipation; decreased sweating; difficulty sleeping; dizziness; enlarged pupils; excessive daytime drowsiness; headache; lack of coordination; lightheadedness; nausea; nervousness; unsteadiness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in heartbeat; decreased urination; decreased sexual ability or desire; diarrhea; difficulty focusing your eyes; fainting; fast heartbeat; fever, chills, or persistent sore throat; involuntary muscle movements; loss of taste; mental or mood changes; overexcitement; overstimulation; pounding in the chest; swelling; unusual weakness; vomiting; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Librax Capsules

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Librax Capsules:

Blurred vision; constipation; drowsiness; dry mouth.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); behavior changes (eg, excessive anger or rage); changes in sexual desire; changes in the menstrual period; confusion; difficulty urinating; excitability; fainting; loss of coordination; sore throat or fever; swelling; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Librax Side Effects - for the Professional

Librax

No side effects or manifestations not seen with either compound alone have been reported with the administration of Librax. However, since Librax contains chlordiazepoxide hydrochloride and clidinium bromide, the possibility of untoward effects which may be seen with either of these two compounds cannot be excluded.

When chlordiazepoxide hydrochloride has been used alone the necessity of discontinuing therapy because of undesirable effects has been rare. Drowsiness, ataxia and confusion have been reported in some patients — particularly the elderly and debilitated. While these effects can be avoided in almost all instances by proper dosage adjustment, they have occasionally been observed at the lower dosage ranges. In a few instances syncope has been reported.

Other adverse reactions reported during therapy with chlordiazepoxide hydrochloride include isolated instances of skin eruptions, edema, minor menstrual irregularities, nausea and constipation, extrapyramidal symptoms, as well as increased and decreased libido. Such side effects have been infrequent and are generally controlled with reduction of dosage. Changes in EEG patterns (low-voltage fast activity) have been observed in patients during and after chlordiazepoxide hydrochloride treatment.

Blood dyscrasias, including agranulocytosis, jaundice and hepatic dysfunction have occasionally been reported during therapy with chlordiazepoxide hydrochloride. When chlordiazepoxide hydrochloride treatment is protracted, periodic blood counts and liver function tests are advisable.

Adverse effects reported with use of Librax are those typical of anticolinergic agents, ie, dryness of the mouth, blurring of vision, urinary hesitancy and constipation. Constipation has occurred most often when Librax therapy has been combined with other spasmolytic agents and/or a low residue diet.

Side Effects by Body System - for Healthcare Professionals

Nervous system

The elderly and debilitated may be more susceptible to the side effects of chlordiazepoxide-clidinium. Drowsiness, ataxia, and confusion have occasionally been reported at the lower dosage ranges.

Nervous system side effects have included drowsiness, ataxia, confusion, and extrapyramidal symptoms. Chlordiazepoxide-clidinium may impair the psychomotor skills necessary for driving. Changes in electroencephalogram (EEG) patterns (low-voltage fast activity) have been reported during and after chlordiazepoxide treatment.

Gastrointestinal

Gastrointestinal side effects have included nausea, constipation, and dryness of the mouth.

Hematologic

Hematologic side effects have included blood dyscrasias (including agranulocytosis).

Hepatic

Hepatic side effects have included jaundice and hepatic dysfunction.

Other

Withdrawal symptoms after abrupt cessation of chlordiazepoxide-clidinium may include dysphoria, insomnia, convulsions, tremor, abdominal and muscle cramps, vomiting, sweating, agitation, restlessness, and anxiety.

Other side effects have included increased and decreased libido, edema, and withdrawal symptoms. Rarely, syncope has been reported.

Ocular

Ocular side effects have included blurring of vision.

Genitourinary

Genitourinary side effects have included minor menstrual irregularities and urinary hesitancy.

Dermatologic

Dermatologic side effects have included skin eruptions.

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