Kapidex Side Effects
Generic name: dexlansoprazole
Note: This document contains side effect information about dexlansoprazole. Some of the dosage forms listed on this page may not apply to the brand name Kapidex.
Some side effects of Kapidex may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to dexlansoprazole: oral capsule delayed release
Along with its needed effects, dexlansoprazole (the active ingredient contained in Kapidex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking dexlansoprazole:Less common
- Acid or sour stomach
- black, tarry stools
- bleeding after defecation
- bleeding from the rectum or bloody stools
- bloated or full feeling
- blurred vision
- burning feeling in the chest or stomach
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- chest pain or discomfort
- chest tightness or heaviness
- continuing diarrhea
- continuing stomach pain
- cracked lips
- decreased urine
- deep or fast breathing with dizziness
- difficult or labored breathing
- dry mouth
- excess air or gas in the stomach
- fast, irregular, pounding, or racing heartbeat or pulse
- feeling of heat
- gaseous abdominal or stomach pain
- headache, severe and throbbing
- incoherent speech
- increased thirst
- increased urination
- joint pain, stiffness, or swelling
- lightheadedness, dizziness, or fainting
- loss of appetite
- metallic taste
- mood changes
- muscle pain or cramps
- muscle weakness
- nausea or vomiting
- numbness or tingling in the hands, feet, or lips
- pain or burning in the throat
- pain or discomfort in the arms, jaw, leg, back, or neck
- pale skin
- passing of gas
- pounding in the ears
- recurrent fever
- redness of the skin
- right upper abdominal or stomach pain and fullness
- shakiness in the legs, arms, hands, or feet
- sores, ulcers, or white spots on the lips, tongue, or inside the mouth
- stomach cramps
- stomach discomfort, fullness, upset, or pain
- swelling of the eyelids, face, lips, hands, or feet
- swollen, painful, or tender lymph glands in the neck, armpit, or groin
- tenderness in the stomach area
- troubled breathing with exertion
- uncomfortable swelling around the anus
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting of blood or material that looks like coffee grounds
- watery or bloody diarrhea
- weight loss
- yellow eyes or skin
- muscle spasms (tetany) or twitching
Some side effects of dexlansoprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common
- Abnormal dreams
- blemishes on the skin
- blistering, crusting, irritation, itching, or reddening of the skin
- body aches or pain
- bumps on the skin
- burning or itching around the anus
- burning while urinating
- change in taste or bad, unusual, or unpleasant (after) taste
- changes in appetite
- changes in menstrual periods
- continuing ringing or buzzing or other unexplained noise in the ears
- cracked, dry, or scaly skin
- decreased interest in sexual intercourse
- decreased sexual ability in males
- difficult or painful urination
- difficulty with moving
- dry, puffy skin
- ear congestion
- ear pain
- excess air or gas in the stomach or intestines
- feeling cold
- feeling of constant movement of self or surroundings
- feeling of warmth
- frequent strong or increased urge to urinate
- general feeling of discomfort or illness
- hearing loss
- heavy bleeding
- hives or welts
- inability to have or keep an erection
- lack or loss of strength
- longer or heavier menstrual periods
- loss in sexual ability, desire, drive, or performance
- loss of voice
- muscle or bone pain
- muscle stiffness
- noisy breathing
- pain around the anus
- pain or tenderness around the eyes and cheekbones
- pain, swelling, or redness in the joints
- painful sexual intercourse
- red, sore eyes
- redness of the face, neck, arms, and occasionally, upper chest
- sensation of spinning
- sore throat
- stuffy or runny nose
- sudden sweating
- thick, white, or curd-like vaginal discharge
- trouble remembering
- trouble sleeping
- unable to sleep
- voice changes
- weight gain
For Healthcare Professionals
Applies to dexlansoprazole: oral delayed release capsule
Gastrointestinal side effects have included diarrhea (4.7% to 5.1%), abdominal pain (3.5% to 4%), nausea (2.8% to 3.3%), vomiting (1.4% to 2.2%), and flatulence (1.4% to 2.6%). Other gastrointestinal side effects reported in clinical studies at an incidence of less than 2% were abnormal feces, anal discomfort, Barrett's esophagus, bezoar, abnormal bowel sounds, breath odor, microscopic colitis, colonic polyp, constipation, dry mouth, duodenitis, dyspepsia, dysphagia, enteritis, eructation, esophagitis, gastric polyp, gastritis, gastroenteritis, gastrointestinal disorders, gastrointestinal hypermotility disorders, GERD, GI ulcers and perforation, hematemesis, hematochezia, hemorrhoids, impaired gastric emptying, irritable bowel syndrome, mucus stools, oral mucosal blistering, painful defecation, proctitis, oral paresthesia, and rectal hemorrhage.
The most common adverse reaction leading to discontinuation of dexlansoprazole in clinical studies was diarrhea (0.7%).
Respiratory side effects have included upper respiratory tract infection (1.7% to 2.9%). Other respiratory side effects reported in clinical studies at an incidence of less than 2% were aspiration, asthma, bronchitis, cough, dyspnea, hiccups, hyperventilation, respiratory tract congestion, and sore throat.
Musculoskeletal side effects reported in clinical studies at an incidence of less than 2% were arthralgia, arthritis, muscle cramps, musculoskeletal pain, bursitis, and myalgia. Postmarketing studies have shown an increased risk of bone fracture.
Metabolic side effects reported in clinical studies at an incidence of less than 2% were appetite changes, hypercalcemia, hypokalemia, dehydration, diabetes mellitus, hyperglycemia, hyperlipidemia, and weight increase. FDA warns that prescription proton pump inhibitor (PPI) drugs may cause low serum magnesium levels (hypomagnesemia) if taken for prolonged periods of time (in most cases, longer than one year). Patients who develop hypomagnesemia may experience seizures, dizziness, abnormal or fast heart beat, or skipped heartbeat, jitteriness, jerking movements or tremors, muscle weakness, spasms of the hands and feet, cramps or muscle aches, and spasm of the voice box.
Cardiovascular side effects reported in clinical studies at an incidence of less than 2% were angina, arrhythmia, bradycardia, tachycardia, chest pain, edema, myocardial infarction, palpitation, hypertension, and vertigo.
Nervous system side effects reported in clinical studies at an incidence of less than 2% were convulsion, dizziness, headaches, migraine, paresthesia, psychomotor hyperactivity, tremor, pain, chills, pyrexia, auditory hallucination, trigeminal neuralgia, restless legs syndrome, and somnolence.
Renal system side effects reported in clinical studies at an incidence of less than 2% were dysuria and micturition urgency.
Psychiatric system side effects reported in clinical studies at an incidence of less than 2% were abnormal dreams, anxiety, depression, insomnia, memory impairment, and libido changes.
Endocrine system side effects reported in clinical studies at an incidence of less than 2% were dysmenorrhea, dyspareunia, menorrhagia, menstrual disorder, hot flushes, hypothyroidism, gout, lymphadenopathy, and goiter.
Ocular system side effects reported in clinical studies at an incidence of less than 2% were eye irritation and eye swelling.
Hematologic system side effects reported in clinical studies at an incidence of less than 2% were anemia, epistaxis, neutropenia, thrombocythemia, increased neutrophils, MCHC decrease, and deep vein thrombosis.
Immunologic system side effects reported in clinical studies at an incidence of less than 2% were candida infections, influenza, pharyngitis, nasopharyngitis, oral herpes, sinusitis, viral infection, herpes zoster, and vulvovaginal infection. Postmarketing immunologic system side effects have included anaphylactic shock (requiring emergency intervention), Stevens-Johnson syndrome, and toxic epidermal necrolysis (some fatal).
Hepatic system side effects reported in clinical studies at an incidence of less than 2% were biliary colic, cholelithiasis, and hepatomegaly.
Dermatologic side effects reported in clinical studies at an incidence of less than 2% were acne, dermatitis, erythema, pruritus, rash, skin lesion, and urticaria.
General side effects reported in clinical studies at an incidence of less than 2% were ear pain, tinnitus, asthenia, chills, mucosal inflammation, nodule, sunburn, dysphonia, folliculitis, tonsillitis, altered taste, oral soft tissue disorder, and feeling abnormal.
Other side effects reported in clinical studies at an incidence of less than 2% were ALP increased, ALT increased, AST increased, bilirubin decreased/increased, blood creatinine increased, blood gastrin increased, liver function test abnormal, platelet count decreased, and total protein increased.
More Kapidex resources
- Kapidex Consumer Overview
- Kapidex Advanced Consumer (Micromedex) - Includes Dosage Information
- Kapidex Delayed-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)
- Kapidex Prescribing Information (FDA)
- Dexlansoprazole Monograph (AHFS DI)
- Dexlansoprazole Professional Patient Advice (Wolters Kluwer)
- Dexilant Prescribing Information (FDA)
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.