Jentadueto Side Effects

Generic Name: linagliptin / metformin

Note: This page contains information about the side effects of linagliptin / metformin. Some of the dosage forms included on this document may not apply to the brand name Jentadueto.

Not all side effects for Jentadueto may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to linagliptin / metformin: oral tablet

In addition to its needed effects, some unwanted effects may be caused by linagliptin / metformin. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking linagliptin / metformin:

Less common
  • Anxiety
  • blurred vision
  • chills
  • cold sweats
  • coma
  • confusion
  • cool, pale skin
  • depression
  • dizziness
  • fast heartbeat
  • headache
  • increased hunger
  • nausea
  • nightmares
  • seizures
  • shakiness
  • slurred speech
  • unusual tiredness or weakness
Incidence not known
  • Bloating
  • constipation
  • darkened urine
  • fainting spells
  • fever
  • indigestion
  • irregular heartbeat
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of appetite
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • vomiting
  • yellow eyes or skin

Some of the side effects that can occur with linagliptin / metformin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Diarrhea
  • excess air or gas in the stomach or intestines
  • full feeling
  • heartburn
  • lack or loss of strength
  • muscle aches
  • passing gas
  • sore throat
  • stuffy or runny nose
Incidence not known
  • Cough
  • decreased appetite
  • difficulty with moving
  • flaking and falling off of the skin
  • hives or welts
  • itching
  • joint pain
  • muscle aching or cramping
  • muscle pains or stiffness
  • redness of the skin
  • skin rash
  • swollen joints

For Healthcare Professionals

Applies to linagliptin / metformin: oral tablet

Respiratory

Respiratory side effects have included cough and nasopharyngitis.

Hypersensitivity

Hypersensitivity side effects have included urticaria, angioedema, bronchial hyperactivity, and localized skin exfoliation.

Musculoskeletal

Musculoskeletal side effects have included myalgia.

Gastrointestinal

Gastrointestinal side effects have included diarrhea, flatulence, indigestion, abdominal discomfort, decreased appetite, nausea, vomiting, and pancreatitis. Postmarketing adverse reactions have included reports of acute pancreatitis, including fatal pancreatitis.

Nervous system

Nervous system side effects have included headache and asthenia.

Dermatologic

Dermatologic side effects have included pruritus.

Metabolic

Metabolic side effects of long-term treatment with metformin has been associated with a decrease in vitamin B12 absorption which may very rarely result in clinically significant vitamin B12 deficiency (e.g., megaloblastic anemia).

Endocrine

Endocrine side effects have included hypoglycemia.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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