Januvia Side Effects

Generic Name: sitagliptin

Note: This page contains side effects data for the generic drug sitagliptin. It is possible that some of the dosage forms included below may not apply to the brand name Januvia.

It is possible that some side effects of Januvia may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to sitagliptin: oral tablet

As well as its needed effects, sitagliptin (the active ingredient contained in Januvia) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking sitagliptin, check with your doctor immediately:

Less common
  • Anxiety
  • blurred vision
  • chills
  • cold sweats
  • confusion
  • cool, pale skin
  • depression
  • dizziness
  • fast heartbeat
  • headache
  • increased hunger
  • loss of consciousness
  • nausea
  • nervousness
  • nightmares
  • seizures
  • shakiness
  • slurred speech
  • unusual tiredness or weakness

Some sitagliptin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Body aches or pain
  • cough
  • difficulty with breathing
  • ear congestion
  • fever
  • loss of voice
  • muscle aches
  • sneezing
  • sore throat
  • stuffy or runny nose
Less common
  • Abdominal or stomach pain
  • diarrhea

For Healthcare Professionals

Applies to sitagliptin: oral tablet

Metabolic

Metabolic side effects have included hypoglycemia.

Gastrointestinal

Gastrointestinal side effects have included abdominal pain, nausea, and diarrhea. Postmarketing experience has included constipation, vomiting, acute pancreatitis, including fatal and nonfatal hemorrhagic and necrotizing pancreatitis.

Respiratory

Respiratory side effects have included nasopharyngitis and upper respiratory tract infection.

Nervous system

Nervous system side effects have included headache.

Hypersensitivity

Hypersensitivity side effects have included anaphylaxis, angioedema, and exfoliative skin conditions including Stevens-Johnson syndrome. Postmarketing hypersensitivity reactions have included rash, urticaria, and cutaneous vasculitis.

Hepatic

Hepatic side effects have included postmarketing reports of hepatic enzyme elevations.

Renal

Renal side effects have included postmarketing reports of worsening renal function, including acute renal failure, sometimes requiring dialysis.

Musculoskeletal

Arthralgia, myalgia, pain in extremities, and back pain have been reported postmarketing.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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