Jakafi Side Effects
Generic name: ruxolitinib
Note: This document contains side effect information about ruxolitinib. Some of the dosage forms listed on this page may not apply to the brand name Jakafi.
Some side effects of Jakafi may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to ruxolitinib: oral tablet
Along with its needed effects, ruxolitinib (the active ingredient contained in Jakafi) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking ruxolitinib:More common
- Black, tarry stools
- bladder pain
- bleeding gums
- blood in the urine or stools
- cloudy urine
- collection of blood under the skin
- deep, dark purple bruise
- difficult, burning, or painful urination
- frequent urge to urinate
- itching, pain, redness, or swelling
- large, flat, blue or purplish patches in the skin
- lower back or side pain
- painful or difficult urination
- pale skin
- pinpoint red spots on the skin
- pus in the urine
- shortness of breath
- small, red or purple spots on the skin
- sore throat
- troubled breathing with exertion
- ulcers, sores, or white spots in the mouth
- unusual bleeding or bruising
- unusual tiredness or weakness
- Painful blisters on the trunk of the body
Some side effects of ruxolitinib may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Bloated or full feeling
- dizziness or lightheadedness
- excess air or gas in the stomach or intestines
- feeling of constant movement of self or surroundings
- passing gas
- sensation of spinning
- weight gain
For Healthcare Professionals
Applies to ruxolitinib: oral tablet
Dermatologic side effects have included bruising (23.2%).
Gastrointestinal side effects have included flatulence (5.2%).
Genitourinary side effects have included urinary tract infections (9.0%).
Hematologic side effects have included anemia (96.1%), thrombocytopenia (69.7%), and neutropenia (18.7%).
Immunologic side effects have included herpes zoster (1.9%).
Metabolic side effects have included weight gain (7.1%).
Laboratory abnormalities have included alanine transaminase (ALT) abnormalities (25.2%), aspartate transaminase (AST) abnormalities (17.4%), and elevated cholesterol levels (16.8%).
Nervous system side effects have included dizziness (18.1%), and headache (14.8%).
More Jakafi resources
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