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Inova 4 / 1 Side Effects

Generic Name: benzoyl peroxide / salicylic acid topical

Note: This page contains information about the side effects of benzoyl peroxide / salicylic acid topical. Some of the dosage forms included on this document may not apply to the brand name Inova 4 / 1.

Not all side effects for Inova 4 / 1 may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to benzoyl peroxide / salicylic acid topical: topical pad

Benzoyl peroxide and salicylic acid topical can cause a rare but serious allergic reaction or severe skin irritation. These reactions may occur just a few minutes after you apply the medicine, or within a day or longer afterward.

Stop using this medicine and Get emergency medical help if you have any of these signs of an allergic reaction while taking benzoyl peroxide / salicylic acid topical: hives, itching; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.

Stop using benzoyl peroxide and salicylic acid topical and call your doctor at once if you have:

  • severe skin irritation after using the medicine;

  • scaly or peeling skin;

  • redness or swelling of treated skin; or

  • nausea, vomiting, diarrhea.

Common side effects may include:

  • dry skin or mild irritation;

  • dizziness; or

  • ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to benzoyl peroxide / salicylic acid topical: topical pad


Excessive drying has been associated with skin peeling, irritation, erythema, and possible edema.[Ref]

Dermatologic side effects have included allergic contact dermatitis and excessive drying (4%).[Ref]


Gastrointestinal side effects including nausea, vomiting, and diarrhea have been reported.[Ref]

Nervous system

Nervous system side effects including dizziness, loss of hearing, tinnitus, and lethargy have been reported.[Ref]


Respiratory side effects including hyperpnea have been reported.[Ref]


1. "Product Information. Inova (benzoyl peroxide topical)." JSJ Pharmaceuticals, Doylestown, PA.

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