Medication Guide App

INOmax Side Effects

Generic Name: nitric oxide

Note: This page contains side effects data for the generic drug nitric oxide. It is possible that some of the dosage forms included below may not apply to the brand name INOmax.

It is possible that some side effects of INOmax may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to nitric oxide: inhalation gas

Nitric oxide causes few side effects, but your baby may have noisy breathing, blood in the urine, or possibly a collapsed lung. There is also a possibility that the baby will have breathing difficulties after the nitric oxide (the active ingredient contained in INOmax) treatment is stopped.

Some of these problems may require further treatment by health care professionals. Your baby will remain under constant supervision during treatment with nitric oxide.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to nitric oxide: inhalation gas

Hematologic

Hematologic side effects including methemoglobinemia (which increases with the dose of nitric oxide (the active ingredient contained in INOmax) have been reported. Elevated NO2 levels have also been reported.

In one study 35% of neonates treated with nitrous oxide 80 ppm had methemoglobin levels exceeding 7%. Following discontinuation or reduction of nitric oxide the methemoglobin levels returned to baseline over a period of hours.

Cardiovascular

Cardiovascular side effects including hypotension (13%) have been reported.

Other

Other side effects including withdrawal (12%), sepsis (7%), infection (6%), and cellulitis (5%) have been reported. Accidental exposure of hospital staff to nitric oxide (the active ingredient contained in INOmax) has been associated with chest discomfort, dizziness, dry throat, dyspnea, and headache.

Respiratory

Respiratory side effects including atelectasis (9%) and stridor (5%) have been reported.

Renal

Renal side effects including hematuria (8%) have been reported.

Metabolic

Metabolic side effects including hyperglycemia (8%) have been reported.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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