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Ilevro Side Effects

Generic Name: nepafenac ophthalmic

Note: This page contains information about the side effects of nepafenac ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Ilevro.

Not all side effects for Ilevro may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to nepafenac ophthalmic: ophthalmic suspension

In addition to its needed effects, some unwanted effects may be caused by nepafenac ophthalmic (the active ingredient contained in Ilevro). In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking nepafenac ophthalmic:

More common
  • Blurred vision
  • change in vision
  • decrease in vision
  • loss of vision
Less common
  • Eye pain
  • itching of the eye
  • swelling and/or redness of the eye and lining of the eyelid

Some of the side effects that can occur with nepafenac ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Feeling of having something in the eye
  • sticky sensation of the eyelids
Less common
  • Change in color vision
  • cough
  • crusting in the corner of the eye
  • difficulty seeing at night
  • dizziness
  • dry eyes
  • fever
  • headache
  • increased sensitivity of the eyes to sunlight
  • nausea or vomiting
  • nervousness
  • pounding in the ears
  • seeing flashes or sparks of light
  • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
  • slow or fast heartbeat
  • stuffy or runny nose
  • tenderness around the eyes and cheekbones
  • tightness of the chest or wheezing
  • troubled breathing

For Healthcare Professionals

Applies to nepafenac ophthalmic: ophthalmic suspension


Ocular side effects associated with administration following cataract surgery have included capsular opacity, decreased visual acuity, foreign body sensation, increased intraocular pressure, and sticky sensation in 5% to 10% of patients. Conjunctival edema, corneal edema, dry eye, lid margin crusting, ocular discomfort, ocular hyperemia, ocular pain, ocular pruritus, photophobia, tearing and vitreous detachment have been reported in 1% to 5% of patients. These effects may be a result of the cataract surgical procedure.[Ref]


Cardiovascular side effects have included hypertension in 1% to 4% of patients.[Ref]


Gastrointestinal side effects have included nausea and vomiting in 1% to 4% of patients.[Ref]


Respiratory side effects have included sinusitis in 1% to 4% of patients.[Ref]


Other side effects have included headache in 1% to 4% of patients.[Ref]


1. "Product Information. Nevanac (nepafenac ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

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