Hydroxyprogesterone Side Effects
Not all side effects for hydroxyprogesterone may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to hydroxyprogesterone: intramuscular oil, intramuscular solution
In addition to its needed effects, some unwanted effects may be caused by hydroxyprogesterone. In the event that any of these side effects do occur, they may require medical attention.
If any of the following side effects occur while taking hydroxyprogesterone, check with your doctor or nurse immediately:More common
- Pain, itching, or swelling at the injection site
- Small lumps at the injection site
- chest pain
- dizziness or lightheadedness
- fast heartbeat
- redness, tenderness, or warmth on the skin
- sudden shortness of breath or troubled breathing
Some of the side effects that can occur with hydroxyprogesterone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common
- Hives or welts
- skin rash
For Healthcare Professionals
Applies to hydroxyprogesterone: compounding powder, intramuscular solution
Genitourinary side effects have included admission for preterm labor, preeclampsia or gestational hypertension, gestational diabetes, and oligohydramnios. Postmarketing side effects include urinary tract infection, cervical incompetence, premature rupture of membranes, cervical dilation, and shortened cervix.
Local side effects have included injection site pain, swelling, pruritus, and nodules. Postmarketing side effects include local injection site reactions of erythema, urticaria, rash, irritation, hypersensitivity, and warmth.
Gastrointestinal side effects have included nausea and diarrhea. Postmarketing side effects include vomiting.
Dermatologic side effects have included pruritus and urticaria. Postmarketing side effects include rash.
Nervous system side effects include postmarketing reports of headache and dizziness.
Respiratory side effects include postmarketing reports of dyspnea and chest discomfort.
Other side effects include postmarketing reports of fatigue, fever, and hot flashes/flushes.
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