Hydroxyprogesterone Side Effects
Not all side effects for hydroxyprogesterone may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to hydroxyprogesterone: intramuscular oil, intramuscular solution
Along with its needed effects, hydroxyprogesterone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking hydroxyprogesterone:More common
- Pain, itching, or swelling at the injection site
- Small lumps at the injection site
- chest pain
- dizziness or lightheadedness
- fast heartbeat
- redness, tenderness, or warmth on the skin
- sudden shortness of breath or troubled breathing
Some side effects of hydroxyprogesterone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Hives or welts
- skin rash
For Healthcare Professionals
Applies to hydroxyprogesterone: compounding powder, intramuscular solution
Genitourinary side effects have included admission for preterm labor, preeclampsia or gestational hypertension, gestational diabetes, and oligohydramnios. Postmarketing side effects include urinary tract infection, cervical incompetence, premature rupture of membranes, cervical dilation, and shortened cervix.
Local side effects have included injection site pain, swelling, pruritus, and nodules. Postmarketing side effects include local injection site reactions of erythema, urticaria, rash, irritation, hypersensitivity, and warmth.
Gastrointestinal side effects have included nausea and diarrhea. Postmarketing side effects include vomiting.
Dermatologic side effects have included pruritus and urticaria. Postmarketing side effects include rash.
Nervous system side effects include postmarketing reports of headache and dizziness.
Respiratory side effects include postmarketing reports of dyspnea and chest discomfort.
Other side effects include postmarketing reports of fatigue, fever, and hot flashes/flushes.
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