Hydrocodone and Acetaminophen Oral Solution Side Effects

Please note - some side effects for Hydrocodone and Acetaminophen Oral Solution may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Hydrocodone and Acetaminophen Oral Solution Side Effects - for the Professional

Hydrocodone and Acetaminophen Oral Solution

Potential effects of high dosage are also listed in the OVERDOSAGE section.

Cardio-Renal

Bradycardia, cardiac arrest, circulatory collapse, renal toxicity, renal tubular necrosis, hypotension.

Central Nervous System/Psychiatric

Anxiety, dizziness, drowsiness, dysphoria, euphoria, fear, general malaise, impairment of mental and physical performance, lethargy, light-headedness, mental clouding, mood changes, psychological dependence, sedation, somnolence progressing to stupor or coma.

Endocrine

Hypoglycemic coma.

Gastrointestinal System

Abdominal pain, constipation, gastric distress, heartburn, hepatic necrosis, hepatitis, occult blood loss, nausea, peptic ulcer, and vomiting.

Genitourinary System

Spasm of vesical sphincters, ureteral spasm, and urinary retention.

Hematologic

Agranulocytosis, hemolytic anemia, iron deficiency anemia, prolonged bleeding time, thrombocytopenia.

Hypersensitivity

Allergic reactions.

Musculoskeletal

Skeletal muscle flaccidity.

Respiratory Depression

Acute airway obstruction, apnea, dose-related respiratory depression, shortness of breath.

Special Senses

Cases of hearing impairment or permanent loss have been reported predominantly in patients with chronic overdose.

Skin

Cold and clammy skin, diaphoresis, pruritus, rash.

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