Homatropine ophthalmic Side Effects

Not all side effects for homatropine ophthalmic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to homatropine ophthalmic: ophthalmic solution

Side effects include:

Elevated IOP, transient stinging, burning. With prolonged administration, local irritation (characterized by follicular conjunctivitis, vascular congestion, edema, exudate, and eczematoid dermatitis ), thirst, dry mouth, increased light sensitivity of eyes.

For Healthcare Professionals

Applies to homatropine ophthalmic: compounding powder, ophthalmic solution

Ocular

Ocular side effects have included transient stinging and burning, eye irritation, and increased sensitivity to light. Prolonged use may produce local irritation characterized by follicular conjunctivitis, vascular congestion, edema, exudate and an eczematoid dermatitis.

Gastrointestinal

Gastrointestinal side effects have included thirst and dry mouth.

Nervous system

Nervous system effects due to chronic use of the drug can lead to a confusional state characterized by delirium, agitation, and rarely coma. This state is associated with use in the pediatric and geriatric age groups.

The specific antidote for this systemic anticholinergic syndrome is injectable physostigmine salicylate.

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