Glycopyrrolate Side Effects
Not all side effects for glycopyrrolate may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to glycopyrrolate: oral solution, oral tablet
In addition to its needed effects, some unwanted effects may be caused by glycopyrrolate. In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking glycopyrrolate:More common
- Body aches or pain
- decrease in the frequency of urination
- decrease in urine volume
- difficulty in passing urine (dribbling)
- difficulty with breathing
- ear congestion
- feeling of warmth
- loss of voice
- nasal congestion
- painful urination
- redness of the face, neck, arms, and occasionally, upper chest
- runny nose
- sore throat
- unusual tiredness or weakness
- Abdominal or stomach discomfort or pain
- abdominal or stomach distension
- chest pain
- dry heaves
- dry mouth
- increase in heart rate
- pain or tenderness around the eyes and cheekbones
- rapid breathing
- shortness of breath or troubled breathing
- stuffy nose
- sunken eyes
- tightness in the chest
- wrinkled skin
If any of the following symptoms of overdose occur while taking glycopyrrolate, get emergency help immediately:
- low blood pressure
- muscle weakness
- trouble breathing
Some of the side effects that can occur with glycopyrrolate may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:Less common
- Altered mood
- attack, assault, or force
- change in taste
- chapped lips
- dry skin
- dry tongue
- excess air or gas in the stomach or intestines
- full feeling
- irregular heartbeats
- loss of taste
- paleness of the skin
- passing gas
- trouble with sleeping
- uncontrolled eye movements
For Healthcare Professionals
Applies to glycopyrrolate: injectable solution, oral solution, oral tablet
Nervous system side effects have included headache, nervousness, drowsiness, dizziness, insomnia, and mental confusion. The elderly appear to be more prone to the anticholinergic effects of glycopyrrolate on the CNS. Seizures have been reported from postmarketing experience.
Cardiovascular side effects have included tachycardia and palpitations. In addition, cardiac arrhythmias, cardiac arrest, hypertension, and hypotension have been reported from postmarketing experience.
Gastrointestinal side effects have included dry mouth, nausea, vomiting, constipation, and feeling bloated.
Genitourinary side effects have included urinary hesitancy, urinary retention, and impotence.
Ocular side effects have included blurred vision, increased ocular tension, cycloplegia, and dilatation of the pupil.
Endocrine side effects have included suppression of lactation.
Dermatologic side effects have included dry mucous membranes and decreased sweating.
General side effects have included weakness, hyperpyrexia, and a loss of taste.
Hypersensitivity side effects have included urticaria and other dermal manifestations.
Immunologic side effects have included anaphylaxis.
Local side effects have included pruritus, edema, erythema, and pain at the injection site.
Respiratory side effects have included nasal congestion, nasal dryness, and sinusitis.
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