Glutamine Side Effects

Some side effects of glutamine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to glutamine: oral capsule, oral powder for reconstitution, oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking glutamine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• chest pain;

• hearing problems; or

• signs of infection such as fever, chills, sore throat, flu symptoms, mouth sores, unusual weakness.

Less serious side effects of glutamine may include:

• nausea, vomiting, stomach pain, gas;

• dry mouth, runny nose;

• swelling in your hands or feet;

• muscle or joint pain, back pain;

• headache, dizziness, tired feeling;

• mild skin rash or itching; or

• increased sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to glutamine: compounding powder, oral capsule, oral powder for reconstitution, oral tablet

Cardiovascular

Cardiovascular side effects have included chest pain (19%) and vascular disorder (11%).

Gastrointestinal

Gastrointestinal side effects have included nausea (13% to 31%), vomiting (11% to 19%), abdominal pain (11% to 25%), tenesmus (6% to 33%), flatulence (22% to 25%), hemorrhoids (6% to 11%), dry mouth (6% to 11%), pancreatitis (6% to 11%), constipation (11%), aggravated Crohn's disease (11%), gastric ulcer (11%), and gastrointestinal fistula (11%).

Musculoskeletal

Musculoskeletal side effects have included back pain (6% to 11%), arthralgia (31% to 44%), and myalgia (11% to 13%).

Respiratory

Respiratory side effects have included rhinitis (7% to 19%), laryngitis (11%), and pharyngitis (11%).

Psychiatric

Psychiatric side effects have included depression (11% to 22%).

Other

Other side effects have included peripheral edema (11% to 81%), facial edema (44% to 50%), generalized edema (13%), enlarged abdomen (11%), pain (6% to 19%), vascular disorder (11%), female breast pain (6% to 11%), vaginal fungal infection (11%), increased sweating (13%) and ear or hearing symptoms (13%).

Immunologic

Immunologic side effects have included fever (6% to 22%), chills (11%), malaise (13%), flu-like disorder (6% to 11%), viral or bacterial infection (6% to 19%), sepsis (6% to 20%), and moniliasis (13%).

Metabolic

Metabolic side effects have included dehydration (11% to 19%), and thirst (11%).

Dermatologic

Dermatologic side effects have included rash (7% to 11%) and skin and appendage disorders (11% to 13%).

Local

Local side effects have included injection site pain and/or injection site reaction (11% to 31%).

Nervous system

Central nervous system side effects have included dizziness (6% to 13%), hypoesthesia (6% to 11%), insomnia (11%) and headache (6% to 11%).

Genitourinary

Genitourinary side effects have included pyelonephritis (11%) and renal calculus (11%).

Hepatic

Hepatic side effects have included abnormal hepatic function (11%).

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