Glutamine Side Effects

Not all side effects for glutamine may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to glutamine: oral capsule, oral packet, oral powder, oral powder for solution, oral powder for suspension, oral tablet

In addition to its needed effects, some unwanted effects may be caused by glutamine. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking glutamine:

Less common
  • Blood in urine
  • changes in skin color
  • chills
  • cold hands and feet
  • confusion
  • cough
  • difficulty swallowing
  • dizziness
  • fainting
  • fast heartbeat
  • fever
  • frequent and painful urination
  • headache
  • hives
  • itching
  • lightheadedness
  • lower back or side pain
  • pain, redness, or swelling in arm or leg
  • puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
  • rapid, shallow breathing
  • shortness of breath
  • skin rash
  • stomach pain
  • sudden decrease in amount of urine
  • tightness in chest
  • unusual tiredness or weakness
  • wheezing

Some of the side effects that can occur with glutamine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Cough or hoarseness
  • frequent urge to defecate
  • straining while passing stool
Less common
  • Abnormal or decreased touch sensation
  • back pain
  • bacterial infection
  • bleeding after defecation
  • bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at site
  • bloated full feeling
  • body aches or pain
  • breast pain, female
  • chest pain
  • change in the color, amount, or odor of vaginal discharge
  • congestion
  • constipation
  • Crohn's disease, aggravated
  • dark urine
  • decreased urination
  • diarrhea
  • difficulty having a bowel movement (stool)
  • difficulty in moving
  • discoloration of fingernails or toenails
  • discouragement
  • dry mouth
  • dryness or soreness of throat
  • ear or hearing symptoms
  • excess air or gas in stomach or intestines
  • feeling sad or empty
  • feeling unusually cold shivering
  • flatulence
  • full or bloated feeling
  • general feeling of discomfort or illness
  • increase in heart rate
  • indigestion
  • irritability
  • joint pain;
  • lack of appetite
  • light-colored stools
  • loss of appetite
  • loss of interest or pleasure
  • muscle aches and pains
  • muscle pain or stiffness
  • nausea
  • pain in joints
  • pain or burning while urinating
  • pains in stomach, side, or abdomen, possibly radiating to the back
  • passing gas
  • pressure in the stomach
  • rash
  • rectal bleeding
  • runny nose
  • shivering
  • sleeplessness
  • sneezing
  • sore throat
  • stomach bloating, burning, cramping, or pain
  • stuffy nose
  • sunken eyes
  • sweating
  • swelling of abdominal or stomach area
  • swelling of face
  • swelling of hands, ankles, feet, or lower legs
  • swollen joints
  • tender, swollen glands in neck;
  • thirst
  • trouble concentrating
  • trouble sleeping
  • trouble in swallowing
  • unable to sleep
  • uncomfortable swelling around anus
  • unpleasant breath odor
  • unusual tiredness or weakness
  • voice changes
  • vomiting
  • vomiting of blood
  • weight loss
  • wrinkled skin
  • yellow eyes or skin

For Healthcare Professionals

Applies to glutamine: compounding powder, oral capsule, oral powder for reconstitution, oral tablet

Cardiovascular

Cardiovascular side effects have included chest pain (19%) and vascular disorder (11%).

Gastrointestinal

Gastrointestinal side effects have included nausea (13% to 31%), vomiting (11% to 19%), abdominal pain (11% to 25%), tenesmus (6% to 33%), flatulence (22% to 25%), hemorrhoids (6% to 11%), dry mouth (6% to 11%), pancreatitis (6% to 11%), constipation (11%), aggravated Crohn's disease (11%), gastric ulcer (11%), and gastrointestinal fistula (11%).

Musculoskeletal

Musculoskeletal side effects have included back pain (6% to 11%), arthralgia (31% to 44%), and myalgia (11% to 13%).

Respiratory

Respiratory side effects have included rhinitis (7% to 19%), laryngitis (11%), and pharyngitis (11%).

Psychiatric

Psychiatric side effects have included depression (11% to 22%).

Other

Other side effects have included peripheral edema (11% to 81%), facial edema (44% to 50%), generalized edema (13%), enlarged abdomen (11%), pain (6% to 19%), vascular disorder (11%), female breast pain (6% to 11%), vaginal fungal infection (11%), increased sweating (13%) and ear or hearing symptoms (13%).

Immunologic

Immunologic side effects have included fever (6% to 22%), chills (11%), malaise (13%), flu-like disorder (6% to 11%), viral or bacterial infection (6% to 19%), sepsis (6% to 20%), and moniliasis (13%).

Metabolic

Metabolic side effects have included dehydration (11% to 19%), and thirst (11%).

Dermatologic

Dermatologic side effects have included rash (7% to 11%) and skin and appendage disorders (11% to 13%).

Local

Local side effects have included injection site pain and/or injection site reaction (11% to 31%).

Nervous system

Central nervous system side effects have included dizziness (6% to 13%), hypoesthesia (6% to 11%), insomnia (11%) and headache (6% to 11%).

Genitourinary

Genitourinary side effects have included pyelonephritis (11%) and renal calculus (11%).

Hepatic

Hepatic side effects have included abnormal hepatic function (11%).

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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