Fomepizole Side Effects

Medically reviewed by Drugs.com. Last updated on Aug 22, 2023.

Applies to fomepizole: parenteral injection concentrate for iv infusion.

Side effects include:

Headache, nausea, dizziness, increased drowsiness, bad/metallic taste.

For Healthcare Professionals

Applies to fomepizole: intravenous solution.

General

The most common adverse events were headache, nausea, dizziness, increased drowsiness, and bad taste/metallic taste.^[Ref]

Gastrointestinal

Very common (10% or more): Nausea (11%)

Common (1% to 10%): Abdominal pain, vomiting, diarrhea, dyspepsia, heartburn^[Ref]

Nervous system

Very common (10% or more): Headache (14%)

Common (1% to 10%): Dizziness, increased drowsiness, bad taste/metallic taste, lightheadedness, seizure, agitation, feeling drunk, vertigo, nystagmus, anxiety, "felt strange", decreased environmental awareness, abnormal smell, roar in ear^[Ref]

Other

Common (1% to 10%): Fever, multiorgan system failure, hangover, speech/visual disturbances^[Ref]

Cardiovascular

Common (1% to 10%): Sinus bradycardia/bradycardia, phlebosclerosis, tachycardia, phlebitis, shock, hypotension^[Ref]

Hematologic

Common (1% to 10%): Eosinophilia/hypereosinophilia, lymphangitis, disseminated intravascular coagulation, anemia^[Ref]

Hepatic

Common (1% to 10%): Transient transaminitis^[Ref]

Local

Common (1% to 10%): Pain during injection, inflammation at injection site, application site reaction^[Ref]

Genitourinary

Common (1% to 10%): Anuria^[Ref]

Respiratory

Common (1% to 10%): Hiccups, pharyngitis^[Ref]

Ocular

Common (1% to 10%): Transient blurred vision^[Ref]

Dermatologic

Common (1% to 10%): Facial flush, rash^[Ref]

Musculoskeletal

Common (1% to 10%): Lumbalgia/backache^[Ref]

Metabolic

Common (1% to 10%): Decreased appetite

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer